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Drug-induced acute pancreatitis: results from the hospital-based Berlin case-control surveillance study of 102 cases.
Author: AndersohnF, BronderE, DourosA, GarbeE, KlimpelA, KreutzR, OckengaJ, ThomaeM
Original Abstract of the Article :
BACKGROUND: Drug toxicity is a well-known cause of acute pancreatitis (AP). Although many drugs have been associated with AP, the magnitude of the risk of most of them remains largely unknown. AIM: To determine the pancreatotoxic risk of a wide range of drugs. METHODS: The hospital-based Berlin ca...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/apt.12461
データ提供:米国国立医学図書館(NLM)
Drug-Induced Acute Pancreatitis: A Case-Control Study in Berlin
This study ventures into the complex world of [pharmacovigilance], a field that seeks to identify and understand [the adverse effects of medications]. Focusing on [drug-induced acute pancreatitis (AP)], the researchers conducted a [hospital-based case-control study] in Berlin to determine [the pancreatotoxic risk of a wide range of drugs]. Through meticulous analysis of [patient data and drug exposure], the study aimed to identify [the drugs most likely to cause AP] and quantify [the associated risks].Quantifying the Pancreatotoxic Risk of Drugs
The results of this study provide valuable information for [clinicians and patients] alike. The researchers identified several drugs with [a significantly increased risk of causing AP], including [azathioprine, fenofibrate, mesalazine, and angiotensin-converting enzyme inhibitors]. These findings highlight [the importance of careful drug monitoring] and [patient education] to minimize [the risk of developing AP]. The study's findings serve as a stark reminder that [drug-induced AP] is a real concern and [awareness and vigilance] are essential for patient safety.Implications for Drug Safety
The study's findings underscore the importance of [informed decision-making] when prescribing medications. Clinicians should be aware of [the potential pancreatotoxic risks associated with certain drugs] and take them into account when [selecting treatment options]. Patients should also be informed about [the potential side effects] of their medications and [report any unusual symptoms] to their healthcare providers. This research provides a valuable resource for [promoting drug safety] and [protecting patients from potential harm].Dr.Camel's Conclusion
This study is like a camel navigating the vast desert of [pharmacovigilance], seeking to understand [the potential risks associated with medications]. The researchers' diligent work has led to [the identification of several drugs with a significantly increased risk of causing AP]. This research is a reminder that [drug safety] is paramount and [continuous vigilance] is essential in ensuring the well-being of [patients worldwide].Date :
- Date Completed 2014-10-07
- Date Revised 2022-04-08
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