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Safety of 13-valent pneumococcal conjugate vaccine in infants and children: meta-analysis of 13 clinical trials in 9 countries.

Author: EminiEmilio A, GruberWilliam C, GurtmanAlejandra, JuergensChristine, LaudatFrance, PattersonScott, ScottDaniel A, ThompsonAllison

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This meta-analysis aims to identify potentially important rare safety events related to the use of 13-valent pneumococcal conjugate vaccine (PCV13) in infants and young children by analyzing safety data from various clinical trials.
Paper Details　
Original Abstract of the Article :
Meta-analyses enable summarization and interpretation of data across clinical trials. When applied to safety data they allow for detection of rare events. Recently, a 13-valent pneumococcal conjugate vaccine (PCV13) was approved in multiple countries worldwide for routine immunization of infants and...See full text at original site
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引用元：
https://doi.org/10.1016/j.vaccine.2013.08.025

データ提供：米国国立医学図書館（NLM）

A Meta-analysis of the Safety of Pneumococcal Conjugate Vaccine

The world of [vaccination] is constantly evolving, and researchers are constantly striving to improve the safety and efficacy of vaccines. Like a camel navigating a shifting desert landscape, researchers must carefully analyze data to ensure the safety of new vaccines. This meta-analysis investigates the safety of a 13-valent pneumococcal conjugate vaccine (PCV13) in infants and young children. The researchers analyzed data from 13 clinical trials in 9 countries to identify any rare safety events associated with PCV13. This research is essential for understanding the potential risks and benefits of this important vaccine.

A Global Perspective on Vaccine Safety

The meta-analysis was conducted to identify potentially clinically important rare safety events associated with PCV13. The researchers used a rigorous approach to analyze data from multiple countries, providing a comprehensive view of the vaccine's safety profile. The study is a valuable resource for healthcare providers and policymakers, as it provides evidence-based information about the risks and benefits of PCV13.

A Camel's Perspective on Vaccines

As a camel, I've witnessed the power of vaccines to protect against diseases. This research reminds me of the importance of scientific rigor in ensuring vaccine safety. By carefully analyzing data and considering potential risks, researchers are working to protect the health of individuals and communities around the world. This research is a testament to the ongoing commitment to improving vaccine safety for all.

Dr. Camel's Conclusion

This meta-analysis provides reassuring evidence on the safety of PCV13, highlighting its potential to contribute to the prevention of pneumococcal disease in infants and young children. It emphasizes the importance of ongoing surveillance and research to monitor the long-term safety of vaccines.

Date :
  1. Date Completed 2014-06-02
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

23973321

DOI: Digital Object Identifier

10.1016/j.vaccine.2013.08.025

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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