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Design and pharmaceutical evaluation of a nano-enabled crosslinked multipolymeric scaffold for prolonged intracranial release of Zidovudine.

Author: ChoonaraYahya E, DanckwertsMichael P, HarilallSheri-lee, IyukeSunny E, KumarPradeep, ModiGirish, PillayViness, TomarLomas K, TyagiCharu, du ToitLisa C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study explores the use of nanomedicine to develop an implantable drug delivery device capable of sustained zidovudine release. The aim is to create a device that provides controlled drug delivery over a prolonged period, reducing side effects.
Paper Details　
Original Abstract of the Article :
Nanomedicine explores and allows for the development of drug delivery devices with superior drug uptake, controlled release and fewer drug side-effects. This study explored the use of nanosystems to formulate an implantable drug delivery device capable of sustained zidovudine release over a prolonge...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.18433/j3r88k

データ提供：米国国立医学図書館（NLM）

Sustained Drug Delivery: A New Oasis in the Desert of HIV Treatment

The field of drug delivery is constantly seeking ways to improve the effectiveness of treatments while minimizing side effects. HIV treatment, a journey through a complex desert landscape, often requires long-term medication. This research explores the development of a nano-enabled, implantable device that could deliver sustained doses of zidovudine, a key drug for HIV treatment.

Nanomedicine: A New Frontier

This research ventures into the exciting realm of nanomedicine, using nanosystems to create innovative drug delivery platforms. It's like creating a miniature oasis within the body, releasing medication slowly and steadily over time. This approach could lead to improved patient outcomes and reduced treatment burden.

Hope for Long-Term HIV Treatment

The development of this implantable device offers a glimmer of hope for those living with HIV. It could potentially revolutionize treatment by providing sustained drug delivery, minimizing the need for frequent medication administration. This would allow patients to live a more fulfilling life, less burdened by the demands of their treatment regimen.

Dr.Camel's Conclusion

This research paves the way for a new era in HIV treatment, potentially transforming the landscape of long-term drug delivery. It's like building a sustainable oasis within the body, providing a steady source of hydration and support for those battling this complex disease.

Date :
  1. Date Completed 2014-03-25
  2. Date Revised 2019-11-12
Further Info :

Pubmed ID

24021294

DOI: Digital Object Identifier

10.18433/j3r88k

Related Literature

Article Analysis
・Side Effects of zidovudine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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