Efficacy of Saccharomyces boulardii on necrotizing enterocolitis or sepsis in very low birth weight infants: a randomised controlled trial.

Author: BenzerDerya, GursoyTugba, KaratekinGuner, OvaliFahri, SerceOzge

Paper Details 
Original Abstract of the Article :
BACKGROUND: Probiotics have strain specific effects and the effects of fungi in preventing diseases in preterm infants have been investigated poorly. Saccharomyces boulardii is a yeast which acts both as a probiotic and a polyamine producer. AIM: The objective of this study was to investigate the e...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.earlhumdev.2013.08.013

データ提供:米国国立医学図書館(NLM)

Saccharomyces Boulardii: A Probiotic for Preterm Infants?

Probiotics, live microorganisms that offer potential health benefits, have been investigated for their ability to prevent various conditions in preterm infants. This research explores the efficacy of Saccharomyces boulardii, a specific type of yeast, in preventing necrotizing enterocolitis (NEC) and sepsis in very low birth weight infants. The authors conducted a randomized, double-blind, placebo-controlled trial to assess the effects of S. boulardii supplementation on the incidence of NEC and sepsis in preterm infants.

Exploring the Potential Benefits of Saccharomyces Boulardii in Preterm Infants

The study, despite a large sample size, did not find a significant difference in the incidence of stage ≥ 2 NEC or death, or stage ≥ 2 NEC or late onset culture-proven sepsis between the S. boulardii and placebo groups. This suggests that S. boulardii supplementation may not be a reliable strategy for preventing NEC or sepsis in very low birth weight infants.

Navigating the Challenges of Preterm Infant Care

This research, though not conclusive, emphasizes the need for further research to fully understand the potential benefits and limitations of probiotics in preterm infant care. Just as a camel adapts to the unique challenges of desert survival, researchers continue to explore innovative solutions for improving the health and well-being of preterm infants.

Dr.Camel's Conclusion

The world of preterm infant care is a delicate landscape, where every decision holds significant weight. This study, like a desert expedition, reminds us of the ongoing journey to find effective interventions for these vulnerable infants. While S. boulardii may not be a universal solution, the pursuit of knowledge continues, driven by the desire to improve the lives of those who need it most.

Date :
  1. Date Completed 2014-06-30
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

24041815

DOI: Digital Object Identifier

10.1016/j.earlhumdev.2013.08.013

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.