The human rotavirus vaccine Rotarix™ in infants: an integrated analysis of safety and reactogenicity.

Author: BuyseHubert, HanHtay Htay, KarkadaNaveen, VinalsCarlota

Paper Details 
Original Abstract of the Article :
An integrated analysis of safety and reactogenicity data was undertaken for 28 randomized, placebo-controlled, double-blind Phase II and III trials (DBRCTs) of the oral live-attenuated human rotavirus vaccine, Rotarix™ (GlaxoSmithKline Vaccines). Healthy infants aged 6-20 wk received 2 or 3 doses of...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181014/

データ提供:米国国立医学図書館(NLM)

The Safety and Reactogenicity of Rotarix™ Rotavirus Vaccine

This study delves into the realm of vaccine safety and efficacy, examining the human rotavirus vaccine Rotarix™. It's like a journey through a vast desert of pathogens, where finding a safe and effective vaccine is crucial to protect against disease. This research analyzes data from clinical trials to assess the safety and reactogenicity of the vaccine, ensuring that it's a reliable shield against the harmful effects of rotavirus.

The researchers reviewed data from 28 clinical trials involving thousands of infants who received either the Rotarix™ vaccine or a placebo. They carefully evaluated the incidence of adverse events, both solicited and unsolicited, as well as serious adverse events. Their meticulous analysis was akin to mapping a desert oasis, ensuring that the vaccine provided a safe and effective haven against rotavirus infection.

The study concluded that Rotarix™ had a safety and reactogenicity profile similar to placebo, offering reassurance that it is a safe and effective vaccine. This discovery is akin to finding a clear path through the desert, offering a safe and reliable route to protect against the dangers of rotavirus infection.

A Safe and Effective Vaccine

The results of this study provide strong evidence for the safety and efficacy of Rotarix™. This is a significant achievement, ensuring that we have a reliable tool to protect infants from the potentially serious consequences of rotavirus infection. It's a vital step towards a healthier future, a beacon of hope in the desert of childhood illnesses.

Protecting Infants from Rotavirus

The Rotarix™ vaccine is a valuable tool for protecting infants from rotavirus infection, a common cause of severe diarrhea in children. This study provides reassurance that the vaccine is safe and effective, offering parents peace of mind and a vital shield against this potentially dangerous illness. It's a testament to the power of vaccines, a reminder that they are a vital resource for preventing disease and ensuring the well-being of our youngest and most vulnerable populations.

Dr.Camel's Conclusion

This study, like a desert explorer carefully navigating a treacherous landscape, provides reassuring evidence for the safety and efficacy of Rotarix™ rotavirus vaccine. The findings demonstrate that this vaccine is a vital tool for protecting infants, a valuable resource in the fight against childhood diseases. This study is a testament to the power of science to find solutions to pressing health challenges, a beacon of hope in the desert of human suffering.

Date :
  1. Date Completed 2015-01-05
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24047799

DOI: Digital Object Identifier

PMC4181014

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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