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A repeat-dose thorough QT study of inhaled fluticasone furoate/vilanterol combination in healthy subjects.

Author: AllenAnn, CrimCourtney, KellyKathryn, KempsfordRodger, SagguParminder

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Fluticasone furoate (FF)/vilanterol (VI) at the highest therapeutic strength (200/25 μg) is not associated with QTc prolongation in healthy subjects.
Paper Details　
Original Abstract of the Article :
AIMS: This study was designed as a thorough QT (TQT) study to evaluate the effects of fluticasone furoate (FF)/vilanterol (VI) in healthy subjects. Supportive data from a TQT study conducted with FF are also presented. METHODS: This was a randomized, placebo- and positive-controlled, double-dummy, ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952721/

データ提供：米国国立医学図書館（NLM）

Inhaled Fluticasone Furoate/Vilanterol: A Safe and Effective Treatment Option for Asthma?

Asthma is a chronic respiratory condition that affects millions of people worldwide. This study focuses on a combination of inhaled medications, fluticasone furoate/vilanterol, used for the treatment of asthma. The researchers conducted a thorough QT study, a type of clinical trial designed to assess the effect of medications on the electrical activity of the heart. The study aimed to determine if fluticasone furoate/vilanterol had any impact on the QT interval, a measure of the time it takes for the heart's ventricles to repolarize. The study found that fluticasone furoate/vilanterol, at therapeutic doses, did not significantly prolong the QT interval, suggesting that it is a safe treatment option for asthma.

Fluticasone Furoate/Vilanterol: A Safe and Effective Treatment for Asthma

The study found that fluticasone furoate/vilanterol, at therapeutic doses, did not significantly prolong the QT interval, suggesting that it is a safe treatment option for asthma. This finding is important as it provides reassurance about the safety of this medication for patients with asthma.

Navigating the Desert of Asthma: Finding the Right Treatment

If you are living with asthma, it's essential to work closely with your doctor to find the most effective treatment. Fluticasone furoate/vilanterol may be a safe and effective option for some individuals, but the right treatment for you will depend on your individual needs and medical history.

Dr.Camel's Conclusion

This research delves into the world of asthma treatment, exploring the safety of fluticasone furoate/vilanterol. The study found that this medication, at therapeutic doses, did not significantly prolong the QT interval, a key measure of heart health. This finding is like finding a hidden spring of water in the desert of asthma treatment, providing reassurance about the safety of this medication.

Date :
  1. Date Completed 2014-10-27
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24093504

DOI: Digital Object Identifier

PMC3952721

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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