Paper Details 
Original Abstract of the Article :
Ospemifene is a non-estrogen agent that exerts tissue-specific estrogen agonistic and weak antagonistic effects (i. e., is a selective estrogen receptor modulator [SERM]). The effects of various once-daily oral doses of ospemifene on bone are examined across 3 studies for 4 or 52 weeks after surgery...See full text at original site
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引用元:
https://doi.org/10.1055/s-0033-1355356

データ提供:米国国立医学図書館(NLM)

Ospemifene: A Bone-Building Oasis in the Desert of Estrogen Deficiency

This study investigates the effects of ospemifene, a selective estrogen receptor modulator (SERM), on bone health in a rat model of osteoporosis, a condition characterized by weakened bones. It's like exploring a desert oasis, where ospemifene acts as a nourishing spring, helping to strengthen bones and prevent further bone loss.

The researchers found that ospemifene treatment significantly increased bone mineral content and density in ovariectomized rats, a model of postmenopausal bone loss. It also improved bone structure, increasing trabecular number and reducing trabecular separation.

This study provides evidence that ospemifene could be a valuable tool for managing osteoporosis, particularly in postmenopausal women. It suggests that ospemifene's bone-building properties could help prevent fractures and improve overall bone health.

Bone-Building Power

This study underscores the potential of ospemifene to improve bone health, offering a potential alternative or supplement to traditional osteoporosis therapies.

Nourishing Your Bones

If you are concerned about bone health, talk to your doctor about the best ways to protect your bones. A healthy diet rich in calcium and vitamin D, regular exercise, and appropriate medical treatment can all contribute to strong bones.

Dr. Camel's Conclusion

This study shows that ospemifene could be a valuable tool for maintaining strong bones in the face of estrogen deficiency. It’s a reminder that even in the desert of hormonal changes, there are resources to help us build and preserve our skeletal foundations.

Date :
  1. Date Completed 2014-09-01
  2. Date Revised 2014-01-15
Further Info :

Pubmed ID

24108389

DOI: Digital Object Identifier

10.1055/s-0033-1355356

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Languages

English

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