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Effects of the selective estrogen receptor modulator ospemifene on bone in rats.
Author: HärkönenP, KangasL, PengZ, VäänänenK
Original Abstract of the Article :
Ospemifene is a non-estrogen agent that exerts tissue-specific estrogen agonistic and weak antagonistic effects (i. e., is a selective estrogen receptor modulator [SERM]). The effects of various once-daily oral doses of ospemifene on bone are examined across 3 studies for 4 or 52 weeks after surgery...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1055/s-0033-1355356
データ提供:米国国立医学図書館(NLM)
Ospemifene: A Bone-Building Oasis in the Desert of Estrogen Deficiency
This study investigates the effects of ospemifene, a selective estrogen receptor modulator (SERM), on bone health in a rat model of osteoporosis, a condition characterized by weakened bones. It's like exploring a desert oasis, where ospemifene acts as a nourishing spring, helping to strengthen bones and prevent further bone loss.
The researchers found that ospemifene treatment significantly increased bone mineral content and density in ovariectomized rats, a model of postmenopausal bone loss. It also improved bone structure, increasing trabecular number and reducing trabecular separation.
This study provides evidence that ospemifene could be a valuable tool for managing osteoporosis, particularly in postmenopausal women. It suggests that ospemifene's bone-building properties could help prevent fractures and improve overall bone health.
Bone-Building Power
This study underscores the potential of ospemifene to improve bone health, offering a potential alternative or supplement to traditional osteoporosis therapies.
Nourishing Your Bones
If you are concerned about bone health, talk to your doctor about the best ways to protect your bones. A healthy diet rich in calcium and vitamin D, regular exercise, and appropriate medical treatment can all contribute to strong bones.
Dr. Camel's Conclusion
This study shows that ospemifene could be a valuable tool for maintaining strong bones in the face of estrogen deficiency. It’s a reminder that even in the desert of hormonal changes, there are resources to help us build and preserve our skeletal foundations.
Date :
- Date Completed 2014-09-01
- Date Revised 2014-01-15
Further Info :
Related Literature
English
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