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[Effects of ambrisentan in treatment of pulmonary arterial hypertension: a pilot study with 15 patients].
Author: BaiLei, HeJing, JiangRong, JiangXin, JingZhi-Cheng, WangLan, WenLi, YanPing, ZhaoQin-hua
Original Abstract of the Article :
OBJECTIVE: To investigate the preliminary efficacy and safety of ambrisentan, a selective endothelin receptor antagonist, in patients with pulmonary arterial hypertension (PAH). METHODS: A total of 15 patients with PAH, including 10 patients with idiopathic PAH and 5 patients with associated connec...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/24113042
データ提供:米国国立医学図書館(NLM)
Hope for Pulmonary Arterial Hypertension: Ambrisentan Shows Promise
Pulmonary arterial hypertension (PAH) is a debilitating condition that constricts the blood vessels leading to the lungs. Like a desert storm, PAH can suffocate the body, making it difficult to breathe and move. This study sought to evaluate the potential of ambrisentan, a selective endothelin receptor antagonist, as a therapeutic agent for PAH. The researchers enrolled 15 patients with PAH and administered ambrisentan for 12 weeks, measuring their progress through a variety of indicators. The results were encouraging, with significant improvements in exercise capacity, reductions in pulmonary artery pressure, and decreases in markers of heart strain.
A Breath of Fresh Air for PAH Patients: Ambrisentan Demonstrates Efficacy
The study provides compelling evidence that ambrisentan can significantly improve the quality of life for PAH patients. The improvements in exercise capacity and reduced pulmonary artery pressure offer a glimmer of hope for those battling this challenging condition. The positive findings suggest that ambrisentan could be a valuable tool in the fight against PAH, providing a much-needed oasis in the desert of this debilitating disease.
Living with PAH: Managing the Challenges
PAH is a complex and challenging condition, requiring careful management to minimize its impact on daily life. This research suggests that ambrisentan may offer a promising treatment option, potentially improving symptoms and quality of life for those living with PAH. It's a reminder that ongoing research and innovation are crucial for finding effective treatments for rare and debilitating conditions.
Dr.Camel's Conclusion
This research offers a ray of hope for those living with PAH. The study's findings suggest that ambrisentan could be a valuable treatment option, potentially improving exercise capacity and reducing pulmonary artery pressure. While more research is needed, this study highlights the importance of ongoing research in finding effective treatments for rare and debilitating conditions.
Date :
- Date Completed 2014-08-14
- Date Revised 2016-11-25
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