Paper Details

  1. Home
  2. Paper Details

New pharmacologic treatments for familial hypercholesterolemia.

Author: CarrollDiane, MaturaLea Ann, McDonoughAnnette

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Lomitapide and mipomersen are new treatments for familial hypercholesterolemia, a genetic disorder causing high cholesterol levels.
Paper Details　
Original Abstract of the Article :
Familial hypercholesterolemias are a group of genetic disorders that cause high levels of low-density lipoprotein (LDL) cholesterol, which can lead to atherosclerosis and premature coronary heart disease. Heart disease is the leading cause of death in U.S. women. A major goal in prevention of cardio...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/24138664

データ提供：米国国立医学図書館（NLM）

New Pharmacologic Treatments for Familial Hypercholesterolemia: A Desert of Lipid Management

The desert of lipid management is a vast and complex terrain, where the delicate balance of cholesterol levels is crucial for cardiovascular health. This study examines the potential of two new pharmacologic treatments, lomitapide and mipomersen, for familial hypercholesterolemia, a genetic disorder characterized by high levels of LDL cholesterol. Researchers explore the efficacy and safety of these new medications in managing this challenging condition.

New Hope for Familial Hypercholesterolemia: Lomitapide and Mipomersen

The study presents lomitapide and mipomersen as potential treatment options for familial hypercholesterolemia. These medications, when used in conjunction with lifestyle modifications, can significantly reduce LDL cholesterol levels and potentially improve cardiovascular health. The study highlights the ongoing search for effective therapies for this genetic disorder, offering hope for individuals struggling with high cholesterol.

Navigating the Desert of High Cholesterol: New Tools for Lipid Management

This study underscores the importance of continued innovation in lipid management, seeking new and effective treatments for challenging conditions like familial hypercholesterolemia. The development of lomitapide and mipomersen provides new tools for managing this disorder, offering hope for improved cardiovascular health. Like skilled explorers seeking new resources in the desert, researchers continue to search for solutions to manage lipid disorders and improve the lives of individuals facing these challenges.

Dr.Camel's Conclusion

The desert of lipid management is a constant challenge, but researchers continue to seek new oases of effective treatments. This study highlights the potential of lomitapide and mipomersen in managing familial hypercholesterolemia, offering hope for individuals struggling with this genetic disorder.

Date :
  1. Date Completed 2015-04-13
  2. Date Revised 2013-10-21
Further Info :

Pubmed ID

24138664

DOI: Digital Object Identifier

S1751-4851(15)30786-8

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.