Paper Details 
Original Abstract of the Article :
INTRODUCTION: Bepotastine besilate 1.5% is a newly approved second-generation topical antihistamine indicated for the pruritus associated with allergic conjunctivitis. In Japan, the oral formulation is approved to manage pruritus associated with allergic rhinitis and urticaria. AREAS COVERED: Bepot...See full text at original site
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引用元:
https://doi.org/10.1517/14656566.2013.849242

データ提供:米国国立医学図書館(NLM)

Bepotastine Besilate: A New Hope for Itching?

The study explores the therapeutic potential of bepotastine besilate, a second-generation topical antihistamine, for managing pruritus (itching). The authors provide an overview of the medication's mechanism of action, clinical trial results, and potential applications for various types of itching.

Scratching the Surface of Pruritus

Bepotastine besilate, a piperidine derivative, has been shown to effectively relieve pruritus associated with allergic conjunctivitis, allergic rhinitis, and urticaria. It acts as a dual-acting antiallergic, antagonizing H1 receptors and stabilizing mast cells to prevent histamine release. Clinical trials have demonstrated the efficacy and safety of bepotastine for pruritus relief, with a favorable side effect profile.

Finding Relief from Itch

This study suggests that bepotastine besilate may be a promising treatment option for various types of itching, particularly allergic conjunctivitis. It highlights the medication's efficacy and safety, offering a potential solution for those struggling with this common and often bothersome symptom.

Dr.Camel's Conclusion

This study presents a compelling case for bepotastine besilate as a potential treatment option for various types of itching. Its dual-acting mechanism, proven efficacy, and favorable safety profile make it a promising alternative for managing pruritus. This research highlights the need for further studies to explore the full potential of bepotastine besilate in treating different types of itching and to understand its long-term effects.

Date :
  1. Date Completed 2014-07-08
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

24191914

DOI: Digital Object Identifier

10.1517/14656566.2013.849242

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SNS
PICO Info
in preparation
Languages

English

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