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Back pain's association with vertebral end-plate signal changes in sciatica.

Author: , KoesBart W, Lycklama à NijeholtGeert J, PeulWilco C, Vleggeert-LankampCarmen L A M, el BarzouhiAbdelilah, van den HoutWilbert B, van der KallenBas F

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

In a randomized clinical trial comparing early surgery with prolonged conservative care for sciatica, undergoing surgery was associated with an increase in vertebral end-plate signal changes (VESC) after one year. However, the presence of VESC was not found to be a significant predictor of disabling back pain. This suggests that VESC may not be a primary cause of disabling back pain in patients with sciatica.
Paper Details　
Original Abstract of the Article :
BACKGROUND CONTEXT: Patients with sciatica frequently experience disabling back pain. One of the proposed causes for back pain is vertebral end-plate signal changes (VESC) as visualized by magnetic resonance imaging (MRI). PURPOSE: To report on VESC findings, changes of VESC findings over time, and...See full text at original site
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引用元：
https://doi.org/10.1016/j.spinee.2013.08.058

データ提供：米国国立医学図書館（NLM）

Vertebral End-Plate Signal Changes and Back Pain in Sciatica: A Randomized Clinical Trial

This randomized clinical trial investigates the association between vertebral end-plate signal changes (VESC) and back pain in patients with sciatica. The researchers assessed VESC findings on magnetic resonance imaging (MRI) in patients with sciatica and correlated these findings with back pain severity. The study revealed [主要な発見] about the relationship between VESC and back pain in patients with sciatica. While the study found a correlation between surgery and increased VESC, it did not find a strong association between VESC and disabling back pain, suggesting that other factors might play a more significant role in back pain experience.

VESC and Back Pain in Sciatica: A Complex Relationship

This research highlights the complex relationship between vertebral end-plate signal changes (VESC) and back pain in patients with sciatica. The observed [研究結果] indicate that VESC might not be a primary driver of disabling back pain in this population. This discovery emphasizes the need for further research to fully understand the interplay between VESC and back pain, potentially leading to more targeted and effective treatment strategies.

Navigating Back Pain: Beyond Anatomical Findings

This research underscores the importance of considering multiple factors beyond anatomical findings when managing back pain. The findings suggest that [日常生活で気をつけるべきことや取り入れるべきこと] can play a crucial role in addressing back pain symptoms and improving functional ability. By adopting a comprehensive approach that addresses both anatomical and functional aspects of back pain, we can work towards providing more effective and holistic care.

Dr. Camel's Conclusion

Just as a camel navigates the desert, we must navigate the complexities of back pain, considering both anatomical and functional factors. This study sheds light on the relationship between vertebral end-plate signal changes and back pain, reminding us that the path to recovery can be multifaceted. We must continue to explore the intricate interplay between these factors, striving to provide patients with the most effective and comprehensive care, enabling them to navigate their pain journey with confidence and resilience, like a camel traversing the vast and challenging desert landscape.
Date :
  1. Date Completed 2014-10-13
  2. Date Revised 2022-03-09
Further Info :

Pubmed ID

24239802

DOI: Digital Object Identifier

10.1016/j.spinee.2013.08.058

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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