First clinical experiences with perampanel--the Kork experience in 74 patients.

Author: BacherMatthias, BastThomas, KornmeierReinhold, KurthChristoph, SchollyJulia, StaackAnke M, SteinhoffBernhard J, WisniewskiIlona

Paper Details 
Original Abstract of the Article :
Perampanel (PER) has been approved for adjunctive treatment of partial-onset seizures in patients age 12 years and older. In Germany, PER was licensed and marketed in September of 2012. At our tertiary referral epilepsy center, a couple of difficult-to-treat patients were awaiting this introduction ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/epi.12492

データ提供:米国国立医学図書館(NLM)

Perampanel for Epilepsy: Early Clinical Experiences

Epilepsy, a neurological disorder characterized by seizures, can be like a violent desert storm, disrupting the delicate balance of the brain. This research delves into the early clinical experiences with perampanel, a new medication for the treatment of epilepsy. The study explores the drug's effectiveness and side effects in a group of patients with difficult-to-treat epilepsy. It's like finding a new oasis in the desert of neurological disorders, offering hope for those who have struggled to find relief.

Perampanel: A Potential Oasis in the Desert of Epilepsy?

The study found that perampanel resulted in a significant reduction in seizure frequency in nearly half of the patients, with 14% becoming seizure-free. It's like finding a wellspring of calm in the midst of a turbulent desert storm, offering a respite from the chaos of seizures.

Navigating the Side Effects

The study also noted potential side effects, such as somnolence and dizziness. It's like navigating a desert path where the heat and sun can cause drowsiness, requiring careful attention and adjustments to avoid pitfalls.

Dr.Camel's Conclusion

This study provides a promising first look at perampanel's potential as a treatment for epilepsy. It's like a lone traveler stumbling upon a hidden oasis in the vast desert of neurological disorders. While further research is needed to fully understand its effectiveness and long-term implications, this early glimpse offers hope for those seeking relief from the debilitating effects of epilepsy.

Date :
  1. Date Completed 2014-03-06
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

24400693

DOI: Digital Object Identifier

10.1111/epi.12492

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.