Paper Details

  1. Home
  2. Paper Details

Mucoadhesive chitosan films as a potential ocular delivery system for ofloxacin: preliminary in vitro studies.

Author: ByrroRicardo Martins D, FancaJuçara R, FaracoAndré Augusto G, LobatoFrancisco Carlos F, RibeiroRaul R, SilvaRodrigo Otávio S, VianaFernando Antônio B, da Silva Cunha-JúniorArmando, de Oliveira FulgêncioGustavo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Ofoxacin-loaded chitosan films were successfully produced and showed antibacterial efficacy against Staphylococcus aureus and Pseudomonas aeruginosa.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: The objective of the study is to evaluate the physical properties, in vitro release profile, and antibacterial efficiency of chitosan films prepared with ofloxacin. PROCEDURE: Mucoadhesive films were prepared by means of a casting and solvent evaporation technique performed in a 2 wt% ac...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/vop.12140

データ提供：米国国立医学図書館（NLM）

Chitosan Films: A New Delivery System for Ofloxacin

This research explores a novel approach to drug delivery for ophthalmic medications, focusing on the development of mucoadhesive chitosan films loaded with ofloxacin, an antibiotic commonly used to treat eye infections. The authors investigated the physical properties, in vitro release profile, and antibacterial efficacy of these films. The study revealed that the chitosan films effectively delivered ofloxacin, exhibiting sustained release and potent antibacterial activity against *Staphylococcus aureus* and *Pseudomonas aeruginosa*. The findings suggest that chitosan films offer a promising platform for developing innovative ophthalmic drug delivery systems.

A Desert of Innovation: New Strategies for Ophthalmic Drug Delivery

The study showcases the potential of chitosan films for developing novel ophthalmic drug delivery systems, offering a promising alternative to conventional eye drops.

A Clear Desert: Protecting Our Eyes

Imagine a desert landscape, where the eyes are susceptible to dust and infection. This study explores a new approach to protecting our eyes, using chitosan films to deliver ofloxacin, an antibiotic commonly used to treat eye infections. The findings suggest that chitosan films offer a promising platform for developing innovative ophthalmic drug delivery systems.

Dr.Camel's Conclusion

This study explores the potential of mucoadhesive chitosan films as a novel delivery system for ofloxacin, an antibiotic commonly used to treat eye infections. The study reveals that the chitosan films effectively delivered ofloxacin, exhibiting sustained release and potent antibacterial activity against *Staphylococcus aureus* and *Pseudomonas aeruginosa*. The findings suggest that chitosan films offer a promising platform for developing innovative ophthalmic drug delivery systems.

Date :
  1. Date Completed 2014-11-03
  2. Date Revised 2014-03-04
Further Info :

Pubmed ID

24428388

DOI: Digital Object Identifier

10.1111/vop.12140

Related Literature

Article Analysis
・Effects of ofloxacin ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.