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Meta-analysis of risk of stroke or transient ischemic attack with dabigatran for atrial fibrillation ablation.

Author: AronowWilbert S, ChatterjeeSaurav, GhoshJoydeep, NairoozRamez, SardarPartha, WetterslevJørn

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Dabigatran, a novel oral anticoagulant, is sometimes used for thromboembolic prevention during atrial fibrillation (AF) ablation. This meta-analysis of 17 observational studies and 1 randomized trial showed that periprocedural dabigatran use was associated with a higher risk of thromboembolic complications, including stroke, compared to warfarin. Dabigatran showed a lower risk of minor bleeding compared to warfarin.
Paper Details　
Original Abstract of the Article :
Dabigatran is a novel oral anticoagulant and may be useful during atrial fibrillation (AF) ablation for prevention of thromboembolic events. However, the benefits and adverse effects of periprocedural dabigatran therapy have not been thoroughly evaluated. A meta-analysis was performed to evaluate th...See full text at original site
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引用元：
https://doi.org/10.1016/j.amjcard.2013.12.027

データ提供：米国国立医学図書館（NLM）

Dabigatran and Atrial Fibrillation Ablation: Weighing the Risks and Benefits

Atrial fibrillation (AF) is a common heart rhythm disorder, and ablation procedures are often used to restore normal heart rhythm. This study delves into the use of dabigatran, a novel anticoagulant, during AF ablation, analyzing the potential risks and benefits. The researchers conducted a meta-analysis of studies comparing dabigatran with warfarin, a traditional anticoagulant, to determine the relative efficacy and safety of each drug.

A Closer Look at Dabigatran's Role in AF Ablation

The study found that periprocedural use of dabigatran for AF ablation was associated with a higher risk of thromboembolic complications, including stroke and transient ischemic attack. These findings suggest that dabigatran may not be the optimal anticoagulant for this specific procedure, despite its potential benefits in other settings.

Navigating Anticoagulation for AF Ablation

The research highlights the importance of careful consideration when selecting anticoagulants for AF ablation procedures. The potential risks and benefits must be weighed carefully to ensure the best possible outcome for each patient.

Dr.Camel's Conclusion

You know, just as a camel must navigate a treacherous desert landscape, clinicians must carefully choose the right path when it comes to anticoagulation during AF ablation. This study provides valuable insights to guide these decisions and ensure the safety of patients.

Date :
  1. Date Completed 2014-05-06
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

24513472

DOI: Digital Object Identifier

10.1016/j.amjcard.2013.12.027

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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