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Epilepsy triggered by mefloquine in an adult traveler to Uganda.

Author: AnghebenAndrea, BisoffiZeno, BuonfrateDora, GobbiFederico, PostiglioneChiara, RossaneseAndrea

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This case report describes a traveler who experienced seizures after taking mefloquine for malaria prophylaxis. The case highlights the potential for mefloquine to cause serious neurological side effects and suggests that it may be considered a second-line choice for short-term travelers.
Paper Details　
Original Abstract of the Article :
We report a case of a traveler who visited Uganda for 8 d, and took mefloquine one tablet/week for malaria prophylaxis. After the second dose, he suffered from two episodes of loss of consciousness with seizures, therefore mefloquine was discontinued. During the flight back after full recovery, seiz...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920231/

データ提供：米国国立医学図書館（NLM）

Mefloquine: A Traveler's Cautionary Tale

Travelers venturing into exotic destinations often face the risk of contracting malaria, a potentially life-threatening disease. Mefloquine, a widely used antimalarial medication, offers protection against this mosquito-borne illness. However, like a treacherous sandstorm in the desert, mefloquine can also cause unexpected side effects. This case report, like a traveler's diary, details the experience of an individual who developed epilepsy after taking mefloquine for malaria prophylaxis.

The Price of Protection: Epilepsy as a Side Effect

The case report describes a traveler who developed seizures after taking mefloquine for malaria prophylaxis. The seizures persisted even after mefloquine was discontinued, highlighting the potential for long-term neurological complications associated with this medication. This case serves as a stark reminder that even seemingly safe medications can have unforeseen consequences, and careful consideration of potential risks is crucial.

Navigating Malaria Prevention: Choosing the Right Path

The case report underscores the importance of weighing the risks and benefits of different malaria prevention strategies. While mefloquine is effective, it carries a higher risk of neurological side effects compared to alternative medications like atovaquone/proguanil and doxycycline. Travelers should consult with healthcare professionals to determine the most appropriate malaria prophylaxis regimen based on their individual needs and travel plans.

Dr.Camel's Conclusion

This case report, like a warning sign in the desert, reminds us of the importance of being aware of potential risks associated with medications. While mefloquine can provide valuable protection against malaria, it's crucial to weigh its benefits against the potential for neurological side effects. Travelers should choose their path carefully, consulting with healthcare professionals to navigate the complexities of malaria prevention.

Date :
  1. Date Completed 2014-02-14
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

24527427

DOI: Digital Object Identifier

PMC3920231

Related Literature

Article Analysis
・Side Effects of atovaquone and proguanil
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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