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Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris.
Author: AldakkakMohammed, CamaraAmadou K S, StoweDavid F
Original Abstract of the Article :
Coronary heart disease is a global malady and it is the leading cause of death in the United States. Chronic stable angina is the most common manifestation of coronary heart disease and it results from the imbalance between myocardial oxygen supply and demand due to reduction in coronary blood flow....See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/24574825
データ提供:米国国立医学図書館(NLM)
Ranolazine: A New Hope for Chronic Angina?
This study examines the [cardiology] realm and evaluates the safety and efficacy of ranolazine for treating chronic angina pectoris. Chronic stable angina is a common manifestation of coronary heart disease and is often treated with nitrates, beta-blockers, and calcium channel blockers. However, some patients continue to experience symptoms. Ranolazine, a relatively new drug, has shown promise in treating chronic angina by inhibiting the late sodium current, potentially reducing intracellular calcium accumulation. The study summarizes the results of clinical trials that demonstrated the efficacy of ranolazine in reducing angina symptoms, highlighting its safety profile and emphasizing the importance of careful consideration for patients with impaired hepatic or renal function.
Ranolazine's Potential: A New Player in Angina Treatment
The study's findings suggest that ranolazine may offer a valuable treatment option for patients with chronic angina who experience persistent symptoms despite traditional therapies. The drug's safety profile and effectiveness in clinical trials make it a promising addition to the arsenal of treatments for angina. However, careful monitoring of patients with liver or kidney impairment is essential to ensure safe and effective use.
Finding Relief: Angina and Treatment Options
Angina can be a debilitating condition, limiting physical activity and quality of life. This research highlights the potential of ranolazine as a new and effective treatment option for patients with chronic angina. The study emphasizes the importance of considering individual patient characteristics and carefully weighing the risks and benefits of different treatment options to ensure optimal care.
Dr.Camel's Conclusion
Angina is a challenging condition, but with the emergence of new treatments like ranolazine, hope is on the horizon. By understanding the nuances of treatment options and carefully monitoring patients, we can strive to improve the lives of those suffering from this debilitating condition.
Date :
- Date Completed n.d.
- Date Revised 2021-10-21
Further Info :
Related Literature
English
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