Sequential RAAS blockade: is it worth the risk?

Author: PerssonFrederik, RossingPeter

Paper Details 
Original Abstract of the Article :
Soon after the emergence of the renin-angiotensin-aldosterone system (RAAS) blocking treatment as the cornerstone of renoprotective treatment in the prevention and treatment of diabetic and nondiabetic CKD, it was investigated if a higher degree of achievable RAAS blockade by combining more than one...See full text at original site
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引用元:
https://doi.org/10.1053/j.ackd.2014.01.003

データ提供:米国国立医学図書館(NLM)

RAAS Blockade: A Balancing Act in Kidney Protection

This study delves into the complex world of renin-angiotensin-aldosterone system (RAAS) blockade, a common approach to protecting the kidneys. It's like a desert journey, where researchers are navigating the delicate balance between benefits and risks. The study examines the practice of combining multiple RAAS blockers to achieve greater blockade, a strategy that has been explored to improve kidney outcomes. However, the authors caution against this approach, citing the potential for adverse effects and the need for careful consideration.

Dual RAAS Blockade: A Balancing Act

This research highlights the need for a cautious approach to dual RAAS blockade. It's like navigating a sandstorm - while there are potential benefits, there are also risks that need to be carefully weighed. The study's findings suggest that the risks of dual RAAS blockade may not outweigh the potential benefits, particularly in light of the disappointing results from major clinical trials.

Understanding the Landscape of Kidney Protection

This study underscores the importance of understanding the intricacies of kidney protection and the potential risks and benefits of various treatment strategies. It's like exploring a desert map - you need to carefully consider the terrain and choose your path wisely. Patients should discuss the risks and benefits of RAAS blockade with their doctors to make informed decisions about their treatment.

Dr.Camel's Conclusion

RAAS blockade is a powerful tool in kidney protection, but like a desert oasis, it needs to be approached with care. This study reminds us that the pursuit of greater blockade may not always lead to the desired outcome. Careful consideration of the risks and benefits, combined with close monitoring, is crucial for achieving the best possible outcomes in kidney health.

Date :
  1. Date Completed 2014-10-31
  2. Date Revised 2014-03-07
Further Info :

Pubmed ID

24602465

DOI: Digital Object Identifier

10.1053/j.ackd.2014.01.003

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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