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[Some practical questions on chronic stipsis treatment with prucalopride].

Author: BarbaraG, BellacosaL, CogliandroR, CremonC, De GiorgioR, StanghelliniV

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Prucalopride, a novel enterokinetic drug, is effective in improving bowel function and relieving digestive symptoms in patients with severe chronic constipation who have not responded to traditional laxatives. It is a selective agonist of 5-HT4 receptors, with low cardiovascular risk and minimal drug interactions.
Paper Details　
Original Abstract of the Article :
Chronic constipation is a frequent pathological condition bearing relevant socioeconomic burdens, mainly due to uncertain management and unsatisfactory response to traditional laxatives. Prucalopride is a novel enterokinetic drug, that has been demonstrated to improve bowel functions and relieve a b...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/24632771

データ提供：米国国立医学図書館（NLM）

Prucalopride: A Novel Treatment for Chronic Constipation

Chronic constipation is a common and often debilitating condition that can significantly impact quality of life. This research focuses on prucalopride, a novel enterokinetic drug, as a potential treatment option for patients with chronic constipation who have failed to respond to traditional laxatives. The authors discuss the practical aspects of chronic constipation treatment, highlighting the benefits of prucalopride, including its selective action on the 5-HT4 receptors in the gastrointestinal tract and its lack of cardiovascular side effects. Prucalopride offers a new hope for patients struggling with chronic constipation, providing a potentially more effective and safer treatment option.

Prucalopride: A Targeted Approach to Constipation Relief

The study's focus on prucalopride's selective action on the 5-HT4 receptors in the gastrointestinal tract demonstrates its potential for targeted relief of constipation symptoms. This approach minimizes the risk of unwanted side effects that can occur with non-selective medications. It's like using a precisely targeted watering system in the desert, ensuring that the water reaches the thirsty plants without wasting precious resources.

A Promise for Relief

The study's discussion of prucalopride's efficacy and safety profile offers a promising avenue for treatment of chronic constipation. It provides a valuable resource for clinicians seeking to provide effective and safe relief for their patients struggling with this challenging condition. It's like finding a hidden oasis of relief in the desert of chronic constipation, offering a source of hope and well-being for patients seeking solutions.

Dr. Camel's Conclusion

This research highlights the potential of prucalopride as a novel treatment option for chronic constipation. The study's focus on the drug's selectivity and safety profile underscores its promise for providing effective and well-tolerated relief for patients struggling with this debilitating condition. This research is a reminder that the desert of constipation research is constantly evolving, with new discoveries emerging to improve the lives of patients.
Date :
  1. Date Completed 2014-07-01
  2. Date Revised 2014-03-17
Further Info :

Pubmed ID

24632771

DOI: Digital Object Identifier

R08Y2014N01A0085

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Languages

Italian

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