Prospective investigation of nimodipine for acute vocal fold paralysis.

Author: KrishnaPriya, MuldoonMatthew F, MuninMichael C, RosenClark A, SmithLibby, YoungVyvy

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Nimodipine has been shown to be beneficial for recovery from acute vocal fold paralysis (AVFP) in an animal model. METHODS: prospective, open-label trial of patients with AVFP was performed using nimodipine. Consecutive patients were evaluated and offered nimodipine therapy. RESULTS:...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1002/mus.24111

データ提供:米国国立医学図書館(NLM)

Nimodipine for Acute Vocal Fold Paralysis

This study dives into the intriguing world of treating acute vocal fold paralysis (AVFP) using nimodipine, a calcium channel blocker. The researchers were motivated by promising results in animal models that suggested nimodipine might be effective in promoting recovery from AVFP. Their study design involved a prospective, open-label trial, meaning that both the researchers and the participants knew which treatment was being administered. This type of study is a good first step in exploring a new treatment approach, but further investigation is needed to confirm the results.

Nimodipine Shows Potential for Treating Vocal Fold Paralysis

The study's findings indicate that nimodipine may significantly increase the recovery rate of purposeful motion in paralyzed vocal folds. The observed recovery rate was three times higher than what's typically reported in historical controls. This is a very encouraging outcome, as current treatment options for AVFP can be limited.

Vocal Fold Paralysis and Nimodipine

If you have been diagnosed with AVFP, it's essential to consult with your doctor about the best course of treatment for you. Nimodipine may be a promising option, but it's crucial to weigh the potential benefits against any potential risks. Remember, just like the sands of the desert, the world of medical treatments can be vast and varied. It's essential to find the path that leads you to optimal health and well-being.

Dr.Camel's Conclusion

The researchers emphasize the need for a larger, randomized controlled trial to definitively assess the efficacy of nimodipine for treating AVFP. This is a wise approach, as it allows for more robust scientific evidence to be gathered. The journey towards understanding the optimal treatment for AVFP is a continuous one, and we must be open to new possibilities while remaining grounded in scientific rigor.

Date :
  1. Date Completed 2014-08-04
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

24639294

DOI: Digital Object Identifier

10.1002/mus.24111

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.