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Drug safety evaluation of sorafenib for treatment of solid tumors: consequences for the risk assessment and management of cancer patients.
Author: AlexandreJerome, BlanchetBenoit, BoissierEmilie, Boudou-RouquettePascaline, CessotAnatole, CoriatRomain, DurandJean-Philippe, GirouxJulie, GoldwasserFrancois, HuillardOlivier, Thomas-SchoemannAudrey, VidalMichel
Original Abstract of the Article :
Sorafenib is a multi-tyrosine kinase inhibitor (TKI). Considerable clinical experience has been accumulated since its first Phase III clinical trial in metastatic renal cancer patients in 2007. The management of its early acute toxicity in fit patients is well known. The management of prolonged trea...See full text at original site
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引用元:
https://doi.org/10.1517/14740338.2014.907270
データ提供:米国国立医学図書館(NLM)
Sorafenib: A Multifaceted Weapon in the Fight Against Solid Tumors
Sorafenib is a multi-tyrosine kinase inhibitor (TKI) that has shown promise in treating various solid tumors. This article delves into the safety evaluation of sorafenib, exploring its potential risks and benefits. It's like navigating a complex desert landscape, where the terrain can be challenging but also rewarding. This review examines the accumulated clinical experience with sorafenib, highlighting its effectiveness and its potential for managing long-term treatment.
The article provides a comprehensive overview of sorafenib's safety profile, including its early acute toxicity and the challenges of managing prolonged treatment. It discusses the various side effects associated with sorafenib, emphasizing the need for careful monitoring and management. Despite the potential risks, the article concludes that sorafenib remains a valuable treatment option for solid tumors, particularly when considering its potential benefits for patients.
Balancing the Risks and Rewards of Sorafenib Therapy
This article offers a balanced perspective on the use of sorafenib in treating solid tumors. It acknowledges the potential side effects and risks while recognizing its therapeutic potential and the positive outcomes it can provide for patients. This information is crucial for healthcare professionals to make informed decisions regarding sorafenib therapy and for patients to understand the potential trade-offs involved.
Implications for Cancer Treatment and Patient Care
This review highlights the importance of careful patient selection, monitoring, and management when considering sorafenib therapy. It emphasizes the need for a multidisciplinary approach, involving oncologists, pharmacists, and other healthcare professionals, to optimize patient care and minimize potential risks. The article underscores the importance of ongoing research to further understand the safety and efficacy of sorafenib and to develop strategies for mitigating potential side effects.
Dr.Camel's Conclusion
Sorafenib is like a desert oasis, offering a haven for patients battling solid tumors. While the journey might involve some challenges, its potential benefits make it a valuable resource in the fight against cancer. This review is a reminder that navigating the complex landscape of cancer treatment requires a careful balance between risk and reward, ensuring that patients receive the best possible care while minimizing potential adverse effects.
Date :
- Date Completed 2014-12-09
- Date Revised 2018-12-02
Further Info :
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