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Heart rate variability and treatment outcome in major depression: a pilot study.

Author: CookIan A, CrumpCaroline, DavydovDmitry M, HunterAimee M, JainFelipe A, LeuchterAndrew F, OttavianiCristina, ShapiroDavid, TartterMolly

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This pilot study investigated the association between resting heart rate variability (HRV) and treatment outcome in major depressive disorder (MDD). Lower relative power of very low frequency (rVLF) HRV at baseline predicted improvement in depressive symptoms in both escitalopram and Iyengar yoga treatment groups. Although vagal parasympathetic measures were correlated with treatment outcome, their predictive power was not significant after adjusting for age and gender. While these findings need further confirmation due to limited sample size, they suggest rVLF as a potential biomarker for predicting MDD treatment response.
Paper Details　
Original Abstract of the Article :
Variations in heart rate variability (HRV) have been associated with major depressive disorder (MDD), but the relationship of baseline HRV to treatment outcome in MDD is unclear. We conducted a pilot study to examine associations between resting baseline HRV and MDD treatment outcome. We retrospecti...See full text at original site
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引用元：
https://doi.org/10.1016/j.ijpsycho.2014.04.006

データ提供：米国国立医学図書館（NLM）

Heart Rate Variability and Treatment Outcome in Major Depression: A Promising Biomarker

The field of [psychiatry] is constantly searching for better ways to diagnose and treat [major depressive disorder (MDD)]. This study explores the potential of [heart rate variability (HRV)] as a predictor of treatment outcome in MDD. The authors investigated the relationship between baseline HRV and response to treatment with [escitalopram] and [Iyengar yoga].

Lower rVLF HRV Predicts Better Treatment Outcome in MDD

The researchers found that lower relative power of very low frequency (rVLF) HRV at baseline was significantly associated with improved depressive symptoms, even after adjusting for age and gender. This finding suggests that [rVLF HRV] may be a valuable biomarker for predicting treatment outcome in MDD.

Navigating the Desert of Depression

Major depressive disorder can feel like a vast and unforgiving desert, with symptoms that can seem overwhelming. This study offers a glimmer of hope, suggesting that [HRV] might be a useful tool for navigating this challenging landscape. It’s like finding a reliable compass – guiding us towards better treatment and management of this prevalent condition.

Dr.Camel's Conclusion

This research presents [rVLF HRV] as a potential biomarker for predicting treatment outcome in MDD. This finding could lead to more personalized treatment approaches, helping individuals find the right path through the desert of depression.

Date :
  1. Date Completed 2015-02-09
  2. Date Revised 2014-06-30
Further Info :

Pubmed ID

24769434

DOI: Digital Object Identifier

10.1016/j.ijpsycho.2014.04.006

Related Literature

Article Analysis
・Effective treatment of iyengar yoga
SNS
PICO Info
in preparation
Languages

English

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