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Response-guided therapy in patients with genotype 1 hepatitis C virus: current status and future prospects.

Author: LawitzEric J, MembrenoFernando E

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Treatment of hepatitis C has evolved significantly with the introduction of direct-acting antiviral agents (DAAs). Response-guided therapy has successfully shortened treatment durations and reduced side effects. With promising new DAAs, interferon-free regimens might become the standard of care.
Paper Details　
Original Abstract of the Article :
On-treatment responses to antiviral therapy are used to determine duration of therapy in patients being treated for genotype 1 hepatitis C virus infection. Such use of response-guided therapy has successfully reduced exposure of patients to the side-effects of pegylated interferon and ribavirin with...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/jgh.12632

データ提供：米国国立医学図書館（NLM）

Navigating Hepatitis C Treatment: The Promise of Response-Guided Therapy

Hepatitis C virus (HCV) infection, a serious liver disease, can be a challenging journey, but advancements in antiviral therapy have brought hope to many. This review explores the role of response-guided therapy, a strategy that tailors treatment duration based on a patient's response to medication, in the management of genotype 1 HCV infection. The authors highlight the potential benefits of this approach, which can reduce exposure to side effects while maintaining treatment success.

A Journey Towards a Cure: The Evolution of Hepatitis C Treatment

The development of direct-acting antiviral agents (DAAs) has revolutionized HCV treatment, offering highly effective and well-tolerated regimens. Response-guided therapy, which allows for adjustments to treatment duration based on viral response, has further improved outcomes.

A Clear Path Forward: The Era of Simple and Effective Treatment

Emerging research suggests that the future of HCV treatment may involve even simpler regimens with high cure rates and minimal side effects. This progress brings a wave of hope to patients, offering a chance to navigate the journey to recovery with greater confidence and comfort.

Dr.Camel's Conclusion

This review highlights the rapid evolution of HCV treatment, driven by the development of DAAs and the application of response-guided therapy. The future holds promising advancements, with simpler regimens and higher cure rates. This journey towards a cure continues to offer hope and reassurance to those affected by HCV infection.

Date :
  1. Date Completed 2015-04-09
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

24852401

DOI: Digital Object Identifier

10.1111/jgh.12632

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English

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