Establishment of a novel clear cell sarcoma cell line (Hewga-CCS), and investigation of the antitumor effects of pazopanib on Hewga-CCS.

Author: ArakiNobuhito, HamadaKenichiro, ImuraYoshinori, ItohKazuyuki, NakaNorifumi, OutaniHidetatsu, TanakaTakaaki, WakamatsuToru, YoshikawaHideki

Paper Details 
Original Abstract of the Article :
Clear cell sarcoma (CCS) is a therapeutically unresolved, aggressive, soft tissue sarcoma (STS) that predominantly affects young adults. This sarcoma is defined by t(12;22)(q13;q12) translocation, which leads to the fusion of Ewing sarcoma gene (EWS) to activating transcription factor 1 (ATF1) gene,...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076438/

データ提供:米国国立医学図書館(NLM)

Hewga-CCS: A New Tool for Clear Cell Sarcoma Research

Clear cell sarcoma (CCS), a rare and aggressive soft tissue sarcoma, presents a significant challenge to oncologists. This study focused on establishing a novel CCS cell line, Hewga-CCS, to facilitate research and development of effective treatments. The authors also investigated the antitumor effects of pazopanib, a tyrosine kinase inhibitor, on the newly established cell line.

Hewga-CCS: A Stepping Stone for CCS Research

The development of Hewga-CCS, a new CCS cell line, provides researchers with a valuable tool to study this rare and aggressive cancer. This cell line will enable a deeper understanding of the disease and facilitate the development of new treatment strategies.

Hope for CCS Patients

While CCS is a formidable opponent, the establishment of Hewga-CCS is a positive step towards developing more effective treatment options. This new cell line, like a well-placed oasis in a vast desert, offers a promising platform for research and exploration, potentially leading to better outcomes for CCS patients.

Dr.Camel's Conclusion

This study provides a glimmer of hope in the desert of CCS research. The development of a new cell line and the investigation of pazopanib's antitumor effects offer valuable insights into the disease and potential treatment strategies. This research, like a camel's determined journey, guides us towards a brighter future for CCS patients.

Date :
  1. Date Completed 2015-03-09
  2. Date Revised 2022-03-10
Further Info :

Pubmed ID

24946937

DOI: Digital Object Identifier

PMC4076438

Related Literature

Article Analysis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.