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Treatment of hyperphosphatemia with bixalomer in Japanese patients on long-term hemodialysis with gastrointestinal symptoms.

Author: ItoKae, KumataChiaki, MatsuzakaKantaro, NakajimaYutaka, OgataHiroaki, ShishidoKanji, TakeshimaAkiko, WakasaMikio

Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Switching from sevelamer hydrochloride to bixalomer in hemodialysis patients significantly reduced gastrointestinal symptoms without affecting serum phosphorus levels or overall health parameters.
Paper Details　
Original Abstract of the Article :
Bixalomer (Bix) is an amine-functional polymer, non-calcium-containing phosphate (P) binder, and has been clinically available in Japan recently. Bix is expected to cause fewer gastrointestinal (GI) side-effects as compared with sevelamer hydrochloride (SH), because of less expansion of Bix in the G...See full text at original site
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引用元：
https://doi.org/10.1111/1744-9987.12229

データ提供：米国国立医学図書館（NLM）

Bixalomer: A New Phosphate Binder for Dialysis Patients

This research examines the effectiveness and tolerability of bixalomer, a non-calcium-containing phosphate binder, in managing hyperphosphatemia in patients on long-term hemodialysis. The study compares bixalomer to sevelamer hydrochloride (SH), another commonly used phosphate binder. The researchers found that bixalomer was effective in controlling phosphate levels and was well tolerated by patients, with fewer gastrointestinal (GI) side effects than SH.

Bixalomer: A Promising Alternative for Phosphate Binding

This study provides evidence for the effectiveness and tolerability of bixalomer in managing hyperphosphatemia in hemodialysis patients. The researchers' findings suggest that bixalomer could be a valuable alternative to SH, particularly for patients experiencing GI side effects with SH. This research highlights the need for effective and well-tolerated treatments for hyperphosphatemia in hemodialysis patients.

Implications for Dialysis Treatment

This research underscores the importance of developing effective and well-tolerated treatments for hyperphosphatemia in hemodialysis patients. The study's findings suggest that bixalomer could be a valuable option, particularly for patients experiencing GI side effects with other phosphate binders. This research could lead to improved treatment options for hemodialysis patients, enhancing their quality of life and overall health.

Dr.Camel's Conclusion

This study is like finding a cool oasis in the midst of the desert of hemodialysis. Bixalomer offers a refreshing and potentially effective alternative to SH, providing a new path to relief for patients struggling with hyperphosphatemia. This research provides a vital tool in our efforts to improve the quality of life for hemodialysis patients.

Date :
  1. Date Completed 2015-02-23
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

24975891

DOI: Digital Object Identifier

10.1111/1744-9987.12229

Related Literature

Article Analysis
・Side Effects of sevelamer
SNS
PICO Info
in preparation
Languages

English

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