Substitution of calcium carbonate for aluminum hydroxide in patients on hemodialysis. Effects on acidosis, on parathyroid function, and on calcemia.

Author: AnelliA, BrancaccioD, DamassoR, GallieniM, GarellaS, PadoveseP

Paper Details 
Original Abstract of the Article :
Substitution of calcium carbonate for aluminum hydroxide in patients on dialysis: effects on acidosis, parathyroid function, and calcemia. We studied the effects of substituting CaCO3 for aluminum-containing gels on metabolic acidosis and on the response of the parathyroid glands in 11 patients trea...See full text at original site
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引用元:
https://doi.org/10.1159/000185614

データ提供:米国国立医学図書館(NLM)

Calcium Carbonate: A New Approach to Dialysis Treatment

Navigating the world of kidney disease, like traversing a vast desert, can be a challenging and often unpredictable journey. This study, a beacon of hope in the desert of dialysis treatment, explores a new approach to managing acidosis and parathyroid function in patients undergoing hemodialysis. The authors investigated the effects of substituting calcium carbonate (CaCO3) for aluminum hydroxide, a common medication used to manage phosphate levels, in patients on dialysis. Their findings suggest that CaCO3 may offer a more effective and safer alternative, highlighting the potential for improved outcomes for dialysis patients.

Calcium Carbonate: A Potential Game Changer

The study's findings suggest that CaCO3, like a refreshing oasis in the desert of dialysis treatment, offers several potential benefits. The authors found that CaCO3 effectively controlled hyperphosphatemia (high phosphate levels) and increased calcium levels while also improving metabolic acidosis. They also observed that CaCO3 administration led to a decrease in plasma aluminum levels, potentially reducing the risk of aluminum toxicity. The study provides valuable insights into the potential advantages of using CaCO3 in dialysis treatment, suggesting a more effective and safer approach.

Managing Acidosis and Parathyroid Function: A Balancing Act

The study's findings highlight the importance of managing acidosis and parathyroid function in dialysis patients. The researchers found that CaCO3 effectively controlled hyperphosphatemia and improved acidosis, but also observed a paradoxical increase in parathyroid hormone (PTH) levels despite increased calcium levels. This suggests that a careful and individualized approach is necessary to optimize treatment and minimize potential complications. The study underscores the importance of ongoing monitoring and adjustments to treatment strategies to ensure the best possible outcomes for dialysis patients.

Dr.Camel's Conclusion

Like a skilled caravan leader navigating a desert, dialysis treatment requires careful attention to detail and a constant awareness of the ever-changing landscape. This study, a compass guiding us through the complexities of dialysis, suggests that calcium carbonate offers a potentially more effective and safer approach. The research underscores the need for ongoing monitoring and individualized treatment plans to optimize outcomes and improve the well-being of dialysis patients.

Date :
  1. Date Completed 1989-08-03
  2. Date Revised 2018-02-15
Further Info :

Pubmed ID

2500612

DOI: Digital Object Identifier

10.1159/000185614

Related Literature

SNS
PICO Info
in preparation
Languages

English

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