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Substitution of calcium carbonate for aluminum hydroxide in patients on hemodialysis. Effects on acidosis, on parathyroid function, and on calcemia.
Author: AnelliA, BrancaccioD, DamassoR, GallieniM, GarellaS, PadoveseP
Original Abstract of the Article :
Substitution of calcium carbonate for aluminum hydroxide in patients on dialysis: effects on acidosis, parathyroid function, and calcemia. We studied the effects of substituting CaCO3 for aluminum-containing gels on metabolic acidosis and on the response of the parathyroid glands in 11 patients trea...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1159/000185614
データ提供:米国国立医学図書館(NLM)
Calcium Carbonate: A New Approach to Dialysis Treatment
Navigating the world of kidney disease, like traversing a vast desert, can be a challenging and often unpredictable journey. This study, a beacon of hope in the desert of dialysis treatment, explores a new approach to managing acidosis and parathyroid function in patients undergoing hemodialysis. The authors investigated the effects of substituting calcium carbonate (CaCO3) for aluminum hydroxide, a common medication used to manage phosphate levels, in patients on dialysis. Their findings suggest that CaCO3 may offer a more effective and safer alternative, highlighting the potential for improved outcomes for dialysis patients.
Calcium Carbonate: A Potential Game Changer
The study's findings suggest that CaCO3, like a refreshing oasis in the desert of dialysis treatment, offers several potential benefits. The authors found that CaCO3 effectively controlled hyperphosphatemia (high phosphate levels) and increased calcium levels while also improving metabolic acidosis. They also observed that CaCO3 administration led to a decrease in plasma aluminum levels, potentially reducing the risk of aluminum toxicity. The study provides valuable insights into the potential advantages of using CaCO3 in dialysis treatment, suggesting a more effective and safer approach.
Managing Acidosis and Parathyroid Function: A Balancing Act
The study's findings highlight the importance of managing acidosis and parathyroid function in dialysis patients. The researchers found that CaCO3 effectively controlled hyperphosphatemia and improved acidosis, but also observed a paradoxical increase in parathyroid hormone (PTH) levels despite increased calcium levels. This suggests that a careful and individualized approach is necessary to optimize treatment and minimize potential complications. The study underscores the importance of ongoing monitoring and adjustments to treatment strategies to ensure the best possible outcomes for dialysis patients.
Dr.Camel's Conclusion
Like a skilled caravan leader navigating a desert, dialysis treatment requires careful attention to detail and a constant awareness of the ever-changing landscape. This study, a compass guiding us through the complexities of dialysis, suggests that calcium carbonate offers a potentially more effective and safer approach. The research underscores the need for ongoing monitoring and individualized treatment plans to optimize outcomes and improve the well-being of dialysis patients.
Date :
- Date Completed 1989-08-03
- Date Revised 2018-02-15
Further Info :
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