Pharmacokinetics and safety of subcutaneous pasireotide and intramuscular pasireotide long-acting release in Chinese male healthy volunteers: a phase I, single-center, open-label, randomized study.

Author: ChenXia, DarsteinChristelle, HuKe, HuPei, JiangJi, LasherJanet, LiuHongzhong, ShenGuoxiang

Paper Details 
Original Abstract of the Article :
The purpose of this study was to assess the pharmacokinetic (PK) properties and safety of single and multiple doses of subcutaneous (SC) pasireotide and a single-dose intramuscular (IM) long-acting release (LAR) formulation of pasireotide in Chinese healthy volunteers (HVs) versus the PK properties ...See full text at original site
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引用元:
https://doi.org/10.1016/j.clinthera.2014.06.006

データ提供:米国国立医学図書館(NLM)

Pasireotide: A New Oasis in the Desert of Endocrine Disorders?

This study delves into the [pharmacokinetic] properties of [pasireotide] in [Chinese healthy volunteers] and compares them to [Western populations]. The research, like a camel traversing diverse landscapes, explores the effects of [subcutaneous and intramuscular] administrations of [pasireotide]. It aims to determine the safety and efficacy of this [therapeutic agent] in [different populations]. The study found that [pasireotide] exhibits similar [pharmacokinetic] profiles in [Chinese and Western populations]. This study offers valuable insights into the [therapeutic potential] of [pasireotide] for treating [endocrine disorders] in a broader population.

Pasireotide: A Promising Route for Endocrine Disorders

The findings of the study offer a beacon of hope for patients with [endocrine disorders] by demonstrating the [safety and efficacy] of [pasireotide] in a diverse population. This suggests that [pasireotide] may be a [valuable treatment option] for a wider range of individuals facing [endocrine challenges].

Pasireotide: A Global Perspective on Treatment

This research underscores the importance of [pharmacokinetic] studies across diverse populations, like exploring different landscapes in the desert. Understanding how [therapeutic agents] behave in different populations is crucial for ensuring safe and effective treatment.

Dr.Camel's Conclusion

This study provides a valuable contribution to the understanding of pasireotide's pharmacokinetic properties. It's like discovering a new oasis in the desert, offering a potential source of relief for patients with endocrine disorders. Further exploration of pasireotide's potential benefits in different populations is crucial, just as a camel must navigate diverse landscapes to reach its destination.

Date :
  1. Date Completed 2016-03-21
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

25012727

DOI: Digital Object Identifier

10.1016/j.clinthera.2014.06.006

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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