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Efficacy of albendazole in combination with thymol against Echinococcus multilocularis protoscoleces and metacestodes.

Author: CelinaElissondo María, MaríaAlbani Clara

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the efficacy of albendazole and thymol, individually and in combination, against Echinococcus multilocularis, a parasite that causes alveolar echinococcosis. The combination of both drugs demonstrated the most potent antiparasitic effect in vitro, suggesting a potential for more effective treatment strategies.
Paper Details　
Original Abstract of the Article :
The larval (metacestode) stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), a mainly hepatic disease characterized by continuous asexual proliferation of metacestodes by exogenous budding, resulting in the tumor-like, infiltrative growth of the parasite lesion. Cu...See full text at original site
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引用元：
https://doi.org/10.1016/j.actatropica.2014.08.007

データ提供：米国国立医学図書館（NLM）

Albendazole and Thymol: A New Alliance in the Fight Against Echinococcus Multilocularis

Echinococcus multilocularis, a parasitic tapeworm responsible for alveolar echinococcosis, is a formidable foe, like a desert sandworm threatening to engulf its host. This study explores the potential of combining albendazole, a commonly used antiparasitic drug, with thymol, a natural compound, to combat this parasite.

The study found that the combination of albendazole and thymol exhibited a synergistic effect against E. multilocularis protoscoleces and metacestodes. This is like discovering a new and potent weapon in the fight against a desert menace, offering a more effective approach to parasite control.

The Power of Synergistic Treatment

The study's findings suggest that combining albendazole and thymol could lead to improved treatment outcomes for alveolar echinococcosis. This is like forming a new and powerful alliance in the desert, combining different forces to overcome a shared enemy.

Health Benefits and Practical Applications

This study provides encouraging evidence for the potential of combining albendazole and thymol in the treatment of alveolar echinococcosis. This new approach could lead to more effective treatments and improved outcomes for individuals infected with this parasitic disease.

Dr. Camel's Conclusion

This study is a testament to the power of collaboration and innovation in the fight against parasitic infections. By combining albendazole and thymol, we can potentially overcome the desert sandworm and create a more secure and healthy future for individuals affected by this devastating disease.

Date :
  1. Date Completed 2015-10-26
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25149355

DOI: Digital Object Identifier

10.1016/j.actatropica.2014.08.007

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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