Comparison of metabolic effects of aripiprazole, quetiapine and ziprasidone after 12 weeks of treatment in first treated episode of psychosis.

Author: AmadoJose Antonio, Ayesa-ArriolaRosa, Crespo-FacorroBenedicto, Garcia-UnzuetaM Teresa, Martínez GarcíaObdulia, Ortiz-Garcia de la FozVictor, Pérez-IglesiasRocio, Suarez-PinillaPaula, Tabares-SeisdedosRafael

Paper Details 
Original Abstract of the Article :
This randomized open-label study compared the incidence of metabolic side effects of aripiprazole, ziprasidone and quetiapine in a population of medication-naïve first-episode psychosis patients. A total of 202 subjects were enrolled. Body weight, body mass index, leptin, fasting lipids and fasting ...See full text at original site
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引用元:
https://doi.org/10.1016/j.schres.2014.07.045

データ提供:米国国立医学図書館(NLM)

Metabolic Effects of Aripiprazole, Quetiapine, and Ziprasidone in First-Episode Psychosis

This randomized, open-label study dives deep into the metabolic effects of three antipsychotic medications: aripiprazole, quetiapine, and ziprasidone. The study aimed to compare the incidence of metabolic side effects in a group of first-episode psychosis patients who were medication-naïve. The researchers enrolled 202 subjects, measuring body weight, body mass index, leptin, fasting lipids, and fasting glycemic parameters at baseline and after three months of treatment. The analysis revealed a significant weight increase in a high proportion of patients across all three drug groups. Patients treated with aripiprazole showed the most substantial weight gain, while ziprasidone had the lowest liability for inducing weight gain and lipid abnormalities. This study provides valuable information about the metabolic risks associated with these antipsychotic medications, highlighting the importance of careful monitoring and individualizing treatment plans.

Navigating the Metabolic Desert of Antipsychotic Treatment

This research is like a compass guiding us through the metabolic desert of antipsychotic treatment. The study highlights the potential risks associated with these medications, providing essential information for making informed decisions about treatment plans. It's important to weigh the potential benefits of antipsychotics against the potential metabolic side effects, and to work closely with healthcare providers to manage these risks.

Maintaining a Healthy Oasis in the Desert of Antipsychotic Treatment

Maintaining a healthy lifestyle is crucial for navigating the desert of antipsychotic treatment. This research emphasizes the importance of diet, exercise, and regular monitoring to minimize metabolic risks. Remember, a healthy lifestyle can create a thriving oasis in the desert of chronic illness.

Dr.Camel's Conclusion

This study serves as a valuable reminder of the complex metabolic landscape of antipsychotic treatment. It highlights the importance of individualizing treatment plans and closely monitoring patients for potential metabolic side effects. Just as a camel adapts to the desert environment, we must be adaptable and vigilant in managing the metabolic consequences of antipsychotic medication.

Date :
  1. Date Completed 2015-07-13
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

25151200

DOI: Digital Object Identifier

10.1016/j.schres.2014.07.045

Related Literature

SNS
PICO Info
in preparation
Languages

English

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