[Tenosynovitis confirmed by MRI during anti-tuberculous treatment suspected due to isoniazid--2 case reports and literature review].

Author: KobayashiNobuyuki, MorinoEriko, SugiyamaHaruto, TakasakiJin, YamamotoKei

Paper Details 
Original Abstract of the Article :
The adverse effects of anti-tuberculosis agents is an important problem for treatment of tuberculosis. We report 2 possible cases of isoniazid-induced tenosynovitis. Case 1: A 49-year-old man with untreated diabetic mellitus presented with hypesthesia and difficulty grasping with his right hand 1 mo...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/25195301

データ提供:米国国立医学図書館(NLM)

The Hidden Dangers of Isoniazid: A Case for MRI in Tuberculosis Treatment

Tuberculosis is a serious disease, and the use of anti-tuberculosis agents is essential for successful treatment. However, these medications can sometimes cause unexpected side effects. This research explores the potential for isoniazid, a common anti-tuberculosis drug, to cause tenosynovitis, a painful inflammation of the tendons. The authors present two case reports of patients who developed tenosynovitis during anti-tuberculosis treatment, highlighting the importance of considering this rare but potentially serious side effect. They also emphasize the role of magnetic resonance imaging (MRI) in diagnosing tenosynovitis, as it can provide detailed images of the tendons and surrounding tissues.

The Importance of Early Detection and Diagnosis

These case reports highlight the importance of recognizing the potential for isoniazid-induced tenosynovitis and the need for prompt diagnosis and intervention. MRI can play a crucial role in early detection, allowing for timely management and minimizing the risk of long-term complications. The study's findings encourage clinicians to be vigilant about potential side effects and to use appropriate diagnostic tools to ensure optimal patient care.

Navigating the Terrain of Tuberculosis Treatment

Imagine tuberculosis treatment as a journey across a rugged, mountainous terrain. While the path is essential for restoring health, there are unforeseen challenges along the way. In this research, the researchers discovered that isoniazid, like a treacherous mountain pass, can cause unexpected side effects, such as tenosynovitis. MRI serves as a valuable tool for navigating these hidden dangers, providing a clear view of the terrain and helping us identify potential problems before they worsen.

Dr. Camel's Conclusion

Tuberculosis treatment is a delicate balancing act. While the goal is to eradicate the disease, we must remain vigilant about potential side effects. This research emphasizes the importance of early detection and diagnosis of tenosynovitis, as it can significantly impact patient outcomes. By utilizing advanced imaging techniques like MRI, we can navigate the challenging terrain of tuberculosis treatment and strive towards the best possible results for our patients.

Date :
  1. Date Completed 2014-09-29
  2. Date Revised 2014-09-08
Further Info :

Pubmed ID

25195301

DOI: Digital Object Identifier

25195301

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PICO Info
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Languages

Japanese

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