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Systemic bioavailability, safety and tolerability of topical ozenoxacin in healthy adult volunteers.

Author: AlbaredaNuria, FebbraroSalvatore, GropperSavion, SantosBenjamin

Clinical Trial, Phase IThe first stage of clinical trials in humans. Evaluates the safety, tolerability, and pharmacokinetics of a new drug/treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This Phase I study examined the systemic bioavailability and safety of topical ozenoxacin in healthy volunteers. No systemic absorption was observed, and ozenoxacin was well tolerated. The most common treatment-related adverse events were application-site reactions (erythema and pruritus), but the differences in local tolerability between ozenoxacin and placebo were not clinically significant.
Paper Details　
Original Abstract of the Article :
A series of Phase I studies was conducted in healthy volunteers to examine the systemic bioavailability and safety of topical ozenoxacin. Study 1 examined increasing single doses (relating to quantity and body surface area) of ozenoxacin 1% ointment. Study 2 compared multiple doses of ozenoxacin 1% ...See full text at original site
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引用元：
https://doi.org/10.2217/fmb.14.82

データ提供：米国国立医学図書館（NLM）

Topical Ozenoxacin: A Desert Oasis for Skin Infections

Skin infections can be a nuisance, like a desert sandstorm that irritates and disrupts the skin's delicate balance. This research explores the safety and effectiveness of topical ozenoxacin, a medication used to treat various skin infections.

The researchers conducted a series of clinical trials to assess the systemic bioavailability, safety, and tolerability of topical ozenoxacin. They found that the medication was well-tolerated and did not cause any significant systemic absorption. This suggests that topical ozenoxacin is a safe and effective treatment option for skin infections.

A Targeted Approach to Skin Infections

This research highlights the potential of topical ozenoxacin for treating skin infections. It's like finding a targeted oasis in the desert of skin infections, offering a solution that directly addresses the source of the problem without causing widespread systemic effects.

A Reminder for Responsible Use

It's important to use topical medications, including ozenoxacin, according to your doctor's instructions. Like navigating a desert, following the right course can help you reach your destination safely and effectively.

Dr.Camel's Conclusion

This research provides evidence for the safety and effectiveness of topical ozenoxacin for treating skin infections. It's a reminder that we can find targeted solutions for our health concerns, like uncovering a refreshing oasis in the desert of skin infections.

Date :
  1. Date Completed 2015-05-18
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

25209519

DOI: Digital Object Identifier

10.2217/fmb.14.82

Related Literature

Article Analysis
・Effects of ozenoxacin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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