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A systematic review of therapeutical approaches in bisphosphonates-related osteonecrosis of the jaw (BRONJ).

Author: BiasottoMatteo, ContardoLuca, Di LenardaRoberto, GobboMargherita, OttavianiGiulia, RupelKatia, TirelliGiancarlo, VescoviPaolo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

The management of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is controversial, with no universally accepted guidelines. This systematic review examines different therapeutic approaches described in the literature to assess their effectiveness.
Paper Details　
Original Abstract of the Article :
The clinical management of bisphosphonate-related osteonecrosis of the jaw (BRONJ) remains controversial. Since universally accepted guidelines have not been released yet, clinicians usually chose the type of treatment according to position papers based on expert opinion, or on empirical experience....See full text at original site
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引用元：
https://doi.org/10.1016/j.oraloncology.2014.08.016

データ提供：米国国立医学図書館（NLM）

Navigating the Shifting Sands of BRONJ

Bisphosphonates, a class of drugs often used to treat osteoporosis, have been a valuable tool in the fight against bone loss. However, like a desert mirage, a rare but serious side effect called bisphosphonate-related osteonecrosis of the jaw (BRONJ) can emerge. This condition, characterized by bone death in the jaw, presents a challenging landscape for both patients and clinicians. This research takes a deep dive into the diverse therapeutic approaches used to manage BRONJ, aiming to create a roadmap through this complex terrain.

Mapping the Terrain of BRONJ Treatments

The authors reviewed numerous studies to identify and evaluate different therapeutic approaches for BRONJ. This research highlights the need for a standardized treatment approach for this condition.

A Guide through the Desert of BRONJ

This study is a valuable resource for clinicians grappling with BRONJ. It provides a comprehensive overview of current treatment options and highlights the need for further research to develop more effective therapies.

Dr.Camel's Conclusion

This research, a comprehensive guide through the shifting sands of BRONJ treatment, illuminates various approaches and underscores the need for standardized protocols. This research is like a beacon of hope, guiding clinicians towards more effective strategies for managing BRONJ.

Date :
  1. Date Completed 2015-08-04
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

25240948

DOI: Digital Object Identifier

10.1016/j.oraloncology.2014.08.016

Related Literature

Article Analysis
・Effective treatment of osteonecrosis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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