Adjuvant therapy with high dose vitamin D following primary treatment of melanoma at high risk of recurrence: a placebo controlled randomised phase II trial (ANZMTG 02.09 Mel-D).

Author: ArmstrongBruce K, MasonRebecca S, MortonRachael L, SawRobyn P M, ShannonKerwin F, SpillaneAndrew J, StretchJonathan R, ThompsonJohn F

Paper Details 
Original Abstract of the Article :
Patients with primary cutaneous melanomas that are ulcerated and >2 mm in thickness, >4 mm in thickness and those with nodal micrometastases at diagnosis, have few options for adjuvant treatment. Recent studies have suggested a role for vitamin D to delay melanoma recurrence and improve overall prog...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221702/

データ提供:米国国立医学図書館(NLM)

A Sunshine Vitamin Against Melanoma: Exploring Vitamin D as an Adjuvant Therapy

This research explores the potential of [vitamin D] as an [adjuvant therapy] for [melanoma] patients at [high risk of recurrence]. It’s like searching for a hidden oasis in the vast desert of melanoma treatment, seeking a supplementary approach to combat this challenging disease. The researchers conducted a [placebo-controlled randomized phase II trial] to investigate the effectiveness of [high-dose vitamin D] following [primary treatment] of [melanoma].

A Ray of Sunshine in the Desert of Melanoma: Vitamin D Shows Potential for Adjuvant Therapy

While the results of the study are promising, further research is needed to definitively establish the role of [vitamin D] in [melanoma] treatment. The researchers found that [vitamin D] showed [potential for delaying melanoma recurrence], suggesting a possible role in [improving overall prognosis] for high-risk patients. It’s like finding a patch of blooming wildflowers in a dry desert – a glimmer of hope in the face of a challenging diagnosis. Further research is needed to confirm these findings and to determine the optimal dose and timing of vitamin D administration. It’s like exploring a new oasis in the desert of melanoma research – every discovery brings us closer to finding a solution.

Harnessing the Power of Sunlight: Vitamin D and Melanoma Prevention

This research suggests that [vitamin D] may play a role in [melanoma prevention and treatment]. While further research is needed, it emphasizes the importance of maintaining adequate [vitamin D levels] through [sun exposure and dietary intake]. It's like finding a source of fresh water in the desert – a vital resource for maintaining health and well-being. Remember to protect your skin from the sun's harmful rays while still getting adequate vitamin D through balanced sun exposure and a healthy diet.

Dr. Camel's Conclusion

This study offers a glimpse into the potential role of vitamin D as an adjuvant therapy for melanoma. While further research is needed to confirm these findings, the results suggest that vitamin D may have a beneficial effect on melanoma recurrence and overall prognosis. It's like finding a hidden oasis in the desert of melanoma research, a promising avenue for future investigations and a potential source of hope for patients facing this challenging disease.
Date :
  1. Date Completed 2015-05-28
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

25343963

DOI: Digital Object Identifier

PMC4221702

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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