Effects of ospemifene on the female reproductive and urinary tracts: translation from preclinical models into clinical evidence.

Author: ArcherDavid F, CarrBruce R, ConstantineGinger D, PinkertonJoAnn V, TaylorHugh S

Paper Details 
Original Abstract of the Article :
Treatment of menopausal symptoms by compounds with tissue-selective estrogen agonist/antagonist effects, often called selective estrogen receptor modulators, has been researched as an alternative to the use of estrogen therapy. These structurally diverse molecules elicit tissue-dependent responses i...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481022/

データ提供:米国国立医学図書館(NLM)

Navigating the Estrogenic Landscape: Exploring Ospemifene for Menopausal Health

This research examines the potential of ospemifene, a selective estrogen receptor modulator (SERM), as a treatment option for menopausal symptoms. The study explores the effects of ospemifene on various hormone-responsive tissues and organs, particularly focusing on the female reproductive and urinary tracts. The authors provide a comprehensive overview of the preclinical and clinical evidence supporting the use of ospemifene for managing postmenopausal health issues, including vaginal atrophy, osteoporosis, and breast cancer prevention. The study highlights the potential of SERMs as an alternative to traditional estrogen therapy, offering targeted benefits with potentially reduced risks.

Ospemifene: A Targeted Approach to Menopausal Health

This study underscores the importance of exploring alternative treatment options for menopausal symptoms, particularly those seeking to avoid the potential risks of traditional estrogen therapy. The research highlights the potential of SERMs like ospemifene to provide targeted benefits with potentially reduced risks. The study's findings encourage further research into the long-term effects and safety of ospemifene, potentially paving the way for more effective and safe management of menopausal health.

Managing Menopausal Symptoms: A Journey of Informed Choices

The study's findings encourage open discussions between women and their healthcare providers about the various treatment options for menopausal symptoms. It emphasizes the importance of personalized care, taking into account individual needs and risk profiles. The research highlights the need for continued research and development to expand the treatment options available for menopausal women, ensuring their well-being and promoting optimal health during this transitional phase of life.

Dr.Camel's Conclusion

This research provides valuable insights into the potential of ospemifene, a SERM, as a targeted treatment option for menopausal symptoms. The study underscores the importance of exploring alternatives to traditional estrogen therapy, highlighting the potential benefits and risks of ospemifene for managing postmenopausal health issues. The research encourages open communication between women and their healthcare providers to ensure informed decision-making and personalized care.

Date :
  1. Date Completed 2016-03-16
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

25423325

DOI: Digital Object Identifier

PMC4481022

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Languages

English

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