Reactogenicity and safety of the human rotavirus vaccine, Rotarix™ in The Philippines, Sri Lanka, and India: a post-marketing surveillance study.

Author: BalasubramanianSundaram, BerezoLennie, BernardoRommel, BravoLulu, ChatterjeePallab, ChitrakaAmarjeet, ChoudhuryJaydeep, CimafrancaLeonard, GargPankaj, Htay HanHtay, KarkadaNaveen, KumarKishore, LiuAixue, MehtaShailesh, SiriwardenePrasanna

Paper Details 
Original Abstract of the Article :
Regulatory bodies in The Philippines, Sri Lanka, and India require post-marketing surveillance to provide additional safety data on Rotarix™ in real-life settings. In such studies conducted in The Philippines (November 2006 to July 2012; NCT00353366), Sri Lanka (November 2008 to August 2009; NCT0077...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896787/

データ提供:米国国立医学図書館(NLM)

Rotarix™ Vaccine: A Safe Oasis in the Desert of Rotavirus Infection

Rotavirus, a common cause of severe diarrhea in infants, is a formidable desert storm, leaving children vulnerable to dehydration and other complications. This research examines the safety and reactogenicity of Rotarix™, a rotavirus vaccine, in real-world settings. The study, conducted in the Philippines, Sri Lanka, and India, involved the administration of two doses of Rotarix™ to infants according to local prescribing information. The researchers monitored for adverse events, both solicited and unsolicited, to assess the vaccine's safety profile.

Protecting Children from the Rotavirus Storm

The study found that Rotarix™ was well-tolerated, with most adverse events being mild and temporary. The most common solicited adverse events were irritability and fever, which are typical reactions to vaccines. The study also revealed that Rotarix™ provided substantial protection against rotavirus infection, acting as a shield against the desert storm. These findings underscore the importance of rotavirus vaccination in protecting infants from this potentially life-threatening disease.

Building a Safe Oasis for Infants

This research offers reassurance to parents and healthcare providers regarding the safety and effectiveness of Rotarix™. The study's findings highlight the crucial role of vaccination in creating a safe oasis for infants, protecting them from the devastating effects of rotavirus infection. It serves as a reminder of the importance of vaccination in promoting public health and safeguarding the well-being of our youngest and most vulnerable citizens.

Dr.Camel's Conclusion

Rotavirus infection can be a dangerous desert storm for infants. This research explores the safety and effectiveness of Rotarix™, a rotavirus vaccine, in real-world settings. The findings show that Rotarix™ is well-tolerated, providing protection against rotavirus infection. It's a reminder of the importance of vaccination in creating a safe oasis for infants, shielding them from this potentially life-threatening disease.

Date :
  1. Date Completed 2015-07-10
  2. Date Revised 2016-12-15
Further Info :

Pubmed ID

25424932

DOI: Digital Object Identifier

PMC4896787

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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