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Autologous platelet concentrates for bisphosphonate-related osteonecrosis of the jaw treatment and prevention. A systematic review of the literature.

Author: Del FabbroMassimo, GallesioGiorgia, MozzatiMarco

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review investigates the potential of autologous platelet concentrates (APC) to improve treatment and prevention of bisphosphonate-related osteonecrosis of the jaw (BRONJ).
Paper Details　
Original Abstract of the Article :
Bisphosphonate related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction consisting of progressive bone destruction in the maxillofacial region of patients under current or previous treatment with a bisphosphonate. Autologous platelet concentrates (APC) demonstrated to enhance bone and so...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejca.2014.10.015

データ提供：米国国立医学図書館（NLM）

Autologous Platelet Concentrates for Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ)

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious adverse drug reaction that can occur in patients taking bisphosphonates. This systematic review explores the potential of autologous platelet concentrates (APC) for treating and preventing BRONJ. APC is a concentrated solution of platelets derived from the patient's own blood. The researchers reviewed the available literature to assess the evidence for using APC in BRONJ. The study found that while APC has shown promise in enhancing bone and soft tissue healing in oral surgery procedures, there is limited evidence to support its use in BRONJ. Further research is needed to determine the efficacy of APC in managing this condition.

Autologous Platelet Concentrates: A Potential Treatment for BRONJ?

This systematic review highlights the potential of APC as a treatment option for BRONJ. However, the study acknowledges the need for further research to confirm its efficacy and safety in managing this condition. It is important to consult with a healthcare professional to discuss all treatment options and make informed decisions regarding BRONJ management.

Managing BRONJ: Seeking Expert Care and Exploring Treatment Options

BRONJ is a serious condition that requires expert medical attention. This systematic review emphasizes the importance of consulting with a healthcare professional to discuss the best treatment options for your individual needs. It is essential to seek care from a specialist experienced in managing BRONJ and to stay informed about the latest research and treatment advancements.

Dr. Camel's Conclusion

This systematic review explores the potential of autologous platelet concentrates (APC) for treating and preventing bisphosphonate-related osteonecrosis of the jaw (BRONJ). Just as a camel adapts to the desert's harsh conditions, researchers are continually seeking new and innovative ways to manage complex medical conditions. While APC shows promise, further research is needed to confirm its efficacy in managing BRONJ.

Date :
  1. Date Completed 2015-04-17
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

25466505

DOI: Digital Object Identifier

10.1016/j.ejca.2014.10.015

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in preparation
Languages

English

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