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Efficacy, effectiveness and side effects of medications used to prevent fractures.

Author: ReidI R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Osteoporosis treatment options are increasingly effective for fracture prevention. However, the long-term efficacy and safety of some treatments, particularly oral bisphosphonates, remain unclear. Atypical femoral fractures are a potential risk with prolonged use of bisphosphonates. Experts recommend re-evaluating the use of bisphosphonates after 5 years to ensure the benefits outweigh the risks.
Paper Details　
Original Abstract of the Article :
There is an increasing number of effective therapies for fracture prevention in adults at risk of osteoporosis. However, shortcomings in the evidence underpinning our management of osteoporosis still exist. Evidence of antifracture efficacy in the groups of patients who most commonly use calcium and...See full text at original site
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引用元：
https://doi.org/10.1111/joim.12339

データ提供：米国国立医学図書館（NLM）

Fracture Prevention: A Balancing Act of Benefits and Risks

Think of bone health as a delicate balancing act, where the forces of bone loss and fracture risk are constantly in play. This research explores the world of fracture prevention, highlighting the growing arsenal of therapies available to combat osteoporosis. While effective medications exist, it's important to consider both their benefits and potential risks.

A Closer Look at Fracture Prevention Therapies

The research sheds light on the efficacy of various drugs in preventing fractures, including alendronate, risedronate, zoledronate, denosumab, teriparatide, strontium ranelate, raloxifene, and ibandronate. While these medications have shown success in clinical trials, long-term data on their safety and efficacy are still being gathered. A key concern is the potential for atypical femoral fractures associated with long-term use of oral bisphosphonates.

Navigating the Risks and Benefits

This research emphasizes the importance of weighing the benefits of fracture prevention medication against their potential risks. Regular monitoring and discussion with your doctor are crucial to make informed decisions about your treatment options.

Dr.Camel's Conclusion

This research reminds us that navigating the world of fracture prevention requires a careful balancing act, considering both the benefits and potential risks of available treatments. It's essential to be proactive in managing bone health and to consult with your doctor for personalized advice.

Date :
  1. Date Completed 2015-09-21
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

25495429

DOI: Digital Object Identifier

10.1111/joim.12339

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English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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