A meta-analysis of randomized controlled trials of the risk of bleeding with apixaban versus vitamin K antagonists.

Author: AtallahRenée, EbergMaria, EisenbergMark J, FilionKristian B, ToumaLahoud

Paper Details 
Original Abstract of the Article :
Apixaban is one of the new oral anticoagulants, which is prescribed as an alternative to vitamin K antagonists (VKAs). Concerns regarding its bleeding profile persist and require further evaluation. Therefore, we conducted a meta-analysis of randomized controlled trials (RCTs) to compare the risks o...See full text at original site
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引用元:
https://doi.org/10.1016/j.amjcard.2014.11.039

データ提供:米国国立医学図書館(NLM)

Apixaban vs. Vitamin K Antagonists: A Camel's Take on Bleeding Risks

In the vast landscape of [cardiovascular medicine], we face the constant challenge of balancing the benefits and risks of anticoagulant therapies. This research delves into the intriguing comparison between apixaban and vitamin K antagonists (VKAs), analyzing the relative risks of bleeding in patients with various conditions. It's like exploring a desert of options, seeking the safest and most effective path for patients.

A Safer Path Through the Desert of Anticoagulation

The study, a beacon of light in the desert of anticoagulant research, found that apixaban was associated with a lower risk of any bleeding and major or clinically relevant nonmajor bleeding compared to VKAs. This is like finding a well-trodden path through the desert, offering a safer and more reliable route for patients.

Navigating the Anticoagulation Desert: A Camel's Advice

This research provides valuable insights for clinicians navigating the complex world of anticoagulant therapies. It's like having a map to guide us through the desert of options, helping us choose the most appropriate treatment for each patient. The study's findings suggest that apixaban may offer a safer alternative to VKAs in certain situations, but further research is still needed to fully understand its long-term effects.

Dr. Camel's Conclusion

This study sheds light on the relative risks and benefits of different anticoagulant therapies. It's like uncovering a hidden oasis in the desert - a source of knowledge that can guide us towards safer and more effective treatment options for patients with cardiovascular conditions.

Date :
  1. Date Completed 2015-04-07
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

25547937

DOI: Digital Object Identifier

10.1016/j.amjcard.2014.11.039

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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