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Safety and efficacy of alirocumab 150 mg every 2 weeks, a fully human proprotein convertase subtilisin/kexin type 9 monoclonal antibody: A Phase II pooled analysis.
Author: DufourRobert, FerrandAnne-Catherine, GipeDaniel, HanotinCorinne, KorenMichael J, McKenneyJames M, RothEli M, WuRichard
Original Abstract of the Article :
Alirocumab, a fully human monoclonal antibody to proprotein convertase subtilisin/kexin type 9, is in Phase III development for the treatment of hypercholesterolemia. In Phase II studies, 150 mg every 2 weeks (Q2W) was the highest Q2W dose studied, and it is currently the highest Q2W dose under deve...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1080/00325481.2015.998987
データ提供:米国国立医学図書館(NLM)
Safety and efficacy of alirocumab 150 mg every 2 weeks, a fully human proprotein convertase subtilisin/kexin type 9 monoclonal antibody: A Phase II pooled analysis
High cholesterol is a silent threat, lurking beneath the surface like a desert sandstorm. This study investigates the safety and efficacy of alirocumab, a new type of medication designed to lower cholesterol levels, in patients with high cholesterol. The researchers pooled data from three Phase II studies to provide a comprehensive assessment of this promising treatment option.
Navigating the Cholesterol Desert
The pooled analysis suggests that alirocumab, when administered at a dose of 150 mg every 2 weeks, is both safe and effective in lowering cholesterol levels. This research provides valuable data for future studies and helps guide clinicians in making informed decisions about the use of alirocumab for patients with high cholesterol.
Combating Cholesterol's Silent Threat
This study offers a valuable tool for clinicians seeking to combat the silent threat of high cholesterol. The findings provide evidence that alirocumab can be a safe and effective treatment option for patients, helping them navigate the challenging terrain of cardiovascular health.
Dr.Camel's Conclusion
This research, like a compass guiding us through the desert of cardiovascular health, provides valuable information about the safety and efficacy of alirocumab. It helps us understand the potential benefits and risks of this new treatment option, paving the way for better management of high cholesterol and improved cardiovascular health for patients.
Date :
- Date Completed 2015-09-08
- Date Revised 2019-12-10
Further Info :
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