Good tolerability, long-term survival and easy management of side effects in a patient with metastatic renal cell carcinoma treated with pazopanib.

Author: Di CesarePamela, FrascaroliMara

Paper Details 
Original Abstract of the Article :
In recent years many new agents have been introduced into clinical practice to treat metastatic renal cell carcinoma. Some of these agents are tyrosine kinase inhibitors, which have different adverse events compared to chemotherapy or immunotherapy. We describe the case of a man treated with pazopan...See full text at original site
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引用元:
https://doi.org/10.1700/1778.19306

データ提供:米国国立医学図書館(NLM)

Pazopanib: A promising treatment option for metastatic renal cell carcinoma

In the vast desert of cancer research, we're constantly searching for oases of hope - treatments that can effectively combat this formidable foe. This study delves into the promising world of pazopanib, a tyrosine kinase inhibitor used in the treatment of metastatic renal cell carcinoma. It's like finding a hidden spring in the middle of the desert - a source of relief for patients facing a challenging diagnosis. The researchers used a case study approach to highlight the efficacy and tolerability of pazopanib, comparing it to traditional chemotherapy and immunotherapy, which often come with a plethora of side effects.

Pazopanib proves its worth

The researchers discovered that pazopanib, when used as first-line therapy, provided a significant and durable response in a patient with lung metastases. This is like finding a way to navigate through a treacherous sandstorm - a path to survival for patients with metastatic renal cell carcinoma. The patient's response was remarkable, demonstrating the potential of pazopanib as a valuable treatment option. The management of side effects was also noteworthy - the patient only experienced dysgeusia (altered taste) and mild diarrhea, a far cry from the harsh realities of traditional cancer treatments. This is like finding a cool breeze in the scorching desert - a welcome respite from the discomfort and challenges associated with cancer therapies.

A ray of hope in the cancer landscape

The researchers successfully controlled the elevation of transaminase levels (liver enzymes) with low-dose corticosteroid administration. This is like using a clever trick to traverse a seemingly insurmountable sand dune. This highlights the importance of careful monitoring and proactive management of potential side effects. The patient's quality of life remained high throughout the treatment, a testament to the efficacy and tolerability of pazopanib. This study shines a beacon of hope in the challenging landscape of cancer treatment, suggesting that pazopanib could offer a viable and effective alternative for patients with metastatic renal cell carcinoma.

Dr.Camel's Conclusion

This study serves as a beacon of hope in the challenging landscape of cancer treatment, suggesting that pazopanib could offer a viable and effective alternative for patients with metastatic renal cell carcinoma. Like a refreshing oasis in the vast desert of cancer research, this study showcases the potential of pazopanib to provide a path to survival and a better quality of life for those facing this daunting diagnosis.
Date :
  1. Date Completed 2015-05-15
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

25688516

DOI: Digital Object Identifier

10.1700/1778.19306

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Languages

English

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