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[Histamine effects on the heart with special reference to cardiac side effects of H2 receptor antagonists].

Author: BallerD, HuchzermeyerH

English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the role of histamine receptors in the human heart and the potential cardiovascular effects of H2-receptor blocking agents. While the physiologic role of histamine in the heart remains unclear, it is a major mediator of arrhythmias during histamine release in pathophysiologic conditions. The review highlights the different pharmacodynamic profiles of cimetidine, ranitidine, and famotidine, with cimetidine being associated with a higher risk of cardiac arrhythmias and bradycardia.
Paper Details　
Original Abstract of the Article :
The existence of cardiac h1- and h2-receptors is evidenced by pharmacologic studies. Despite of the relatively high content of cardiac histamine it is not clarified whether histamine actually plays a physiologic role - apart from pharmacologic effects - in the regulation of myocardial function and c...See full text at original site
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引用元：
https://doi.org/10.1007/BF01745343

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 1989-10-12
  2. Date Revised 2019-07-11
Further Info :

Pubmed ID

2570178

DOI: Digital Object Identifier

10.1007/BF01745343

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Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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