Safety and immunogenicity of 23-valent pneumococcal polysaccharide vaccine in 2 to 70 year old healthy people in China: A phase III double blind, randomized clinical trial.

Author: HuYuemei, LiGuifan, LiHong, LiangQi, ShiJichun, WeiWenjin, YeQiang, ZhuFengcai

Paper Details 
Original Abstract of the Article :
To evaluate the safety and immunogenicity of 23-valent pneumococcal polysaccharide vaccine (PPV23), a randomized, double-blind and parallel controlled clinical trial was conducted in Yancheng, Jiangsu Province of China. There were 1200 subjects randomized into 2 groups with a 1:1 allocation. Subject...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514320/

データ提供:米国国立医学図書館(NLM)

Pneumococcal Polysaccharide Vaccine: A Shield Against Infection

This study examines the safety and immunogenicity of a 23-valent pneumococcal polysaccharide vaccine (PPV23). It's like building a protective wall around an oasis, shielding it from the threats of desert storms. The authors conducted a randomized clinical trial in China to evaluate the effectiveness of PPV23 in protecting against pneumococcal infections.

A Protective Oasis: The Effectiveness of PPV23

The study found that PPV23 showed good immunogenicity and tolerability in healthy individuals aged 2 to 70 years. The vaccine effectively induced an immune response against a wide range of pneumococcal serotypes, potentially offering protection against pneumococcal infections. The authors suggest that PPV23 is a safe and effective vaccine for use in this population.

Protecting the Oasis: The Importance of Vaccination

This study underscores the importance of vaccination in preventing pneumococcal infections, a leading cause of serious diseases worldwide. It's like building a network of wells to protect an oasis from drought. Vaccination plays a crucial role in safeguarding public health and reducing the burden of infectious diseases.

Dr. Camel's Conclusion

This research reinforces the importance of vaccination in protecting individuals against pneumococcal infections. It demonstrates the safety and effectiveness of PPV23 in promoting a robust immune response. Just as a camel needs to find a reliable source of water to survive in the desert, we need to rely on effective vaccines to protect ourselves against the threats of infectious diseases.

Date :
  1. Date Completed 2015-12-22
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

25714798

DOI: Digital Object Identifier

PMC4514320

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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