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Lubiprostone in constipation: clinical evidence and place in therapy.

Author: ScheyRon, WilsonNicholas

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Lubiprostone is a prostaglandin-derived bicyclic fatty acid available for the long-term treatment of constipation. Randomized, double-blind, placebo-controlled trials have shown it to be effective and free of serious adverse effects.
Paper Details　
Original Abstract of the Article :
Constipation is one of the most common function bowel disorders encountered by primary care providers and gastroenterologists. Disorders of chronic constipation, including irritable bowel syndrome with constipation, chronic idiopathic constipation, and opioid-induced chronic constipation, are associ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331234/

データ提供：米国国立医学図書館（NLM）

Lubiprostone: A Promising Treatment for Constipation

This research explores the clinical evidence supporting the use of lubiprostone, a prostaglandin-derived bicyclic fatty acid, for the treatment of constipation. The study reviews randomized controlled trials demonstrating the effectiveness and safety of lubiprostone in patients with chronic constipation, irritable bowel syndrome with constipation, and opioid-induced constipation. The authors highlight the potential of lubiprostone as a long-term treatment option for constipation, offering relief from symptoms and improving quality of life.

Lubiprostone: A Potential Solution for Chronic Constipation

The study highlights the effectiveness of lubiprostone in treating various types of constipation, including chronic idiopathic constipation, irritable bowel syndrome with constipation, and opioid-induced constipation. The authors emphasize the safety profile of lubiprostone, with the most common side effects being mild to moderate nausea and diarrhea. This research offers promising insights into the potential benefits of lubiprostone for patients struggling with constipation.

Finding Relief from Constipation: Seeking the Right Treatment

This research emphasizes the importance of seeking appropriate treatment for constipation, especially for those experiencing chronic symptoms. The study highlights the potential of lubiprostone as a safe and effective long-term treatment option, offering relief from symptoms and improving quality of life. It's like finding a refreshing oasis in the desert of digestive discomfort, offering relief and a sense of well-being.

Dr.Camel's Conclusion

This research is like a camel caravan discovering a hidden oasis in the vast desert of digestive discomfort. Lubiprostone offers a potential solution for chronic constipation, providing relief from symptoms and improving quality of life. It's a promising avenue for treatment, offering a refreshing respite from the challenges of constipation.
Date :
  1. Date Completed 2015-03-02
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

25729555

DOI: Digital Object Identifier

PMC4331234

Related Literature

Article Analysis
・Side Effects of lubiprostone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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