Fatal lactic acidosis possibly related to ganciclovir therapy in a renal transplant patient?

Author: HantsonPhilippe, MorelleJohann, VincentMarie-Françoise, WitteboleXavier

Paper Details 
Original Abstract of the Article :
Ganciclovir is widely prescribed in renal transplant patients for the prevention or treatment of herpes and cytomegalovirus (CMV) infections. Side-effects are usually represented by hematological disorders, and particularly leucopenia. We report a case of severe and fatal lactic acidosis developing ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366919/

データ提供:米国国立医学図書館(NLM)

Ganciclovir and Lactic Acidosis: A Cautionary Tale

Ganciclovir is a powerful antiviral drug used to prevent and treat infections in transplant patients, but like a powerful desert wind, it can have unexpected consequences. This case study explores a fatal case of lactic acidosis in a renal transplant patient who received ganciclovir for CMV pneumonia. The study suggests a potential link between ganciclovir and lactic acidosis, highlighting the importance of careful monitoring and a thorough understanding of this potential side effect. This study is like a warning sign in the desert of medication, urging caution and careful consideration of the potential risks associated with certain drugs.

Ganciclovir and Lactic Acidosis: A Potential Link

The case study suggests a potential link between ganciclovir therapy and fatal lactic acidosis. While further research is needed to confirm this association, it underscores the importance of vigilant monitoring of patients receiving ganciclovir. It's like a compass in the desert of medication, guiding healthcare professionals to navigate the potential risks and ensure patient safety.

Navigating the Risks of Antiviral Therapy

This case study serves as a stark reminder of the potential risks associated with antiviral therapy. It highlights the importance of careful monitoring, early detection of complications, and a multidisciplinary approach to patient care. It's like navigating a treacherous desert, requiring vigilance, expertise, and a commitment to patient safety.

Dr.Camel's Conclusion

This case study emphasizes the importance of ongoing vigilance in managing antiviral medications. It highlights the need for careful monitoring and prompt intervention to mitigate potential complications like lactic acidosis. Just as a camel adapts to the challenges of the desert, healthcare professionals must be prepared to navigate the potential risks and ensure the safety of their patients.

Date :
  1. Date Completed 2015-03-26
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

25810616

DOI: Digital Object Identifier

PMC4366919

Related Literature

SNS
PICO Info
in preparation
Languages

English

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