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[Management of side effects of targeted therapies in renal cancer: iatrogenic side effects].

Author: HermineOlivier, MassardChristophe, PatardJean-Jacques, RavaudAlain

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
English AbstractA summary of a research paper/publication written in English for a wider audience.

Overview

Temsirolimus should be used with caution in patients with a history of hypersensitivity to H1 antihistamines. Potential drug interactions are possible with sunitinib, sorafenib, and pazopanib. The combination of bevacizumab and sunitinib is contraindicated unless part of a clinical trial. Screening for hypothyroidism, anemia, and other comorbidities is recommended.
Paper Details　
Original Abstract of the Article :
Since premedication of patients with an H1 antihistamine is recommended before the start of the intravenous infusion of temsirolimus, temsirolimus is to be used with caution in cases where there is a history of hypersensitivity to this class of antihistamines, or medical contra-indication for treatm...See full text at original site
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引用元：
https://doi.org/10.1684/bdc.2011.1447

データ提供：米国国立医学図書館（NLM）

Managing Side Effects of Targeted Therapies in Renal Cancer: A Guide Through the Treatment Desert

The treatment of renal cancer is a complex and ever-evolving journey. This research delves into the management of side effects associated with targeted therapies, highlighting the importance of careful monitoring and proactive interventions. The study emphasizes the need for premedication with H1 antihistamines before administering temsirolimus, especially for patients with hypersensitivity to this class of drugs. The authors also caution against potential drug interactions with other medications and highlight the importance of screening for and managing potential comorbidities, such as hypothyroidism and anemia.

Navigating the Side Effects of Treatment

This research provides valuable insights into the challenges of managing side effects associated with targeted therapies for renal cancer. The authors emphasize the importance of careful monitoring, premedication, and proactive interventions to minimize the impact of these side effects on patients' quality of life.

A Roadmap for Better Treatment

This research underscores the importance of comprehensive and individualized care for patients undergoing targeted therapies for renal cancer. By understanding and proactively addressing potential side effects, healthcare professionals can help patients navigate this challenging journey and achieve the best possible outcomes.

Dr.Camel's Conclusion

The treatment of renal cancer is often a long and winding journey through a desert of challenges. This research provides a roadmap for managing the side effects of targeted therapies, offering practical guidance for healthcare professionals and offering hope to patients navigating this complex terrain.

Date :
  1. Date Completed 2015-03-31
  2. Date Revised 2015-03-30
Further Info :

Pubmed ID

25819130

DOI: Digital Object Identifier

10.1684/bdc.2011.1447

Related Literature

Article Analysis
・Side Effects of temsirolimus
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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