Paper Details
- Home
- Paper Details
The unsolved case of "bone-impairing analgesics": the endocrine effects of opioids on bone metabolism.
Author: ColuzziFlaminia, MattiaConsalvo, PergolizziJoseph, RaffaRobert B
Original Abstract of the Article :
The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased risk of falls caused by central nervous system ef...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386765/
データ提供:米国国立医学図書館(NLM)
Opioids and Bones: A Desert of Unintended Consequences
The use of opioids for chronic pain management has become increasingly prevalent, raising concerns about potential long-term health consequences, including bone health. This research explores the potential endocrine effects of opioids on bone metabolism, hypothesizing that opioids may contribute to increased fracture risk through several mechanisms, including falls, direct effects on bone cells, and hormonal imbalances.
An Oasis of Understanding: Opioids and Bone Metabolism
The study's findings suggest that chronic opioid use may negatively impact bone health, particularly in the context of opioid-induced androgen deficiency. The researchers emphasize the importance of monitoring patients taking chronic opioid therapy for early detection of hormonal impairment and low bone density.
Navigating the Sands of Chronic Pain Management
Imagine a desert traveler seeking relief from persistent pain. Opioids, while offering a temporary respite, may also have unforeseen consequences for bone health. This research highlights the importance of careful monitoring and proactive management to minimize the risks associated with long-term opioid use.
Dr.Camel's Conclusion
This research raises important concerns about the potential impact of chronic opioid use on bone health. The study's findings underscore the need for vigilant monitoring of patients taking opioids, especially for hormonal imbalances and bone density, to mitigate the risks associated with long-term opioid therapy.
Date :
- Date Completed 2015-04-07
- Date Revised 2022-03-11
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.