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Terbinafine: novel formulations that potentiate antifungal activities.

Author: ChenX, GuanS, MaY

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Topical delivery of terbinafine offers several advantages over oral administration for treating dermatophytic infections and onychomycosis, including reduced systemic exposure and improved patient compliance. This review explores novel topical formulations based on polymers and nanostructure carriers that enhance terbinafine delivery and efficacy while minimizing adverse effects.
Paper Details　
Original Abstract of the Article :
Terbinafine, an orally and topically active antifungal agent, has been available for the treatment of dermatophytic infections and onychomycosis for more than a decade. In addition, oral administration has been shown to be associated with drug-drug interactions, hepatotoxicity, low concentration at ...See full text at original site
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引用元：
https://doi.org/10.1358/dot.2015.51.3.2295906

データ提供：米国国立医学図書館（NLM）

Revolutionizing Terbinafine Delivery: A New Era of Antifungal Treatment

This research explores the exciting world of antifungal treatment, focusing on terbinafine, a medication commonly used for fungal infections. The researchers, like explorers navigating a vast desert of drug delivery challenges, sought to develop novel formulations that enhance terbinafine's efficacy and safety. Their findings, like oases in the desert, offer promising solutions to the limitations of current treatment approaches. They propose that topical formulations, like refreshing springs in a parched land, can provide sustained drug delivery to the infected site, minimizing systemic exposure and potential side effects.

Optimizing Antifungal Treatment: A Journey of Innovation

This research highlights the need for innovative drug delivery approaches to optimize antifungal treatment. The study's findings, like a map guiding us through the desert of drug delivery challenges, suggest that topical formulations can provide a safer and more effective way to deliver terbinafine. This shift in delivery method could revolutionize antifungal treatment, leading to improved patient outcomes and enhanced quality of life.

A New Frontier in Antifungal Therapy

The research paves the way for a new era of antifungal treatment. By developing novel formulations that enhance terbinafine delivery, researchers can overcome the limitations of traditional approaches and provide patients with a more effective and well-tolerated treatment option. This innovation holds promise for improving the lives of individuals battling fungal infections, offering them a brighter future free from discomfort and complications.

Dr. Camel's Conclusion

This research, like a camel caravan traversing the desert of pharmaceutical innovation, highlights the exciting potential of novel formulations to enhance terbinafine delivery. The findings offer a beacon of hope for patients battling fungal infections, promising a more effective and safer treatment experience.
Date :
  1. Date Completed 2015-10-16
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25876563

DOI: Digital Object Identifier

10.1358/dot.2015.51.3.2295906

Related Literature

Article Analysis
・Side Effects of terbinafine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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