A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements.

Author: PowersChelsea N, SetzerWilliam N

Paper Details 
Original Abstract of the Article :
PURPOSE: The purpose of this study is to use a molecular docking approach to identify potential estrogen mimics or anti-estrogens in phytochemicals found in popular dietary herbal supplements. METHODS: In this study, 568 phytochemicals found in 17 of the most popular herbal supplements sold in the ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397262/

データ提供:米国国立医学図書館(NLM)

Herbal Supplements: Hidden Estrogenic Effects

This study explores the potential estrogenic effects of phytochemicals found in popular dietary herbal supplements, using a molecular docking approach to identify compounds that may interact with the estrogen receptor. The researchers analyzed a wide range of herbal supplements, identifying several compounds that exhibited strong binding affinity to the estrogen receptor, suggesting potential estrogenic or anti-estrogenic activity.

Hidden Estrogenic Effects: A Potential for Concern

The study reveals that many popular herbal supplements, like hidden oases in the vast desert of dietary choices, may contain compounds that can interact with the estrogen receptor. This finding raises concerns about potential unintended consequences of using these supplements, as estrogenic activity can have a range of effects on the body. The study emphasizes the need for further research to understand the long-term implications of these interactions and to develop strategies for mitigating potential risks.

Understanding the Landscape of Dietary Choices

This research underscores the importance of understanding the potential effects of dietary supplements, particularly those marketed for women's health. It highlights the need for careful consideration of ingredients and potential interactions with the body's hormonal systems. This is like navigating a desert landscape, being aware of potential pitfalls and hidden dangers. The study emphasizes the need for more research to ensure the safety and efficacy of herbal supplements and to educate consumers about potential risks and benefits.

Dr.Camel's Conclusion

This study, like a camel caravan venturing through a desert of dietary choices, reveals the potential for hidden estrogenic effects from popular herbal supplements. The researchers found that many supplements contain compounds that can interact with the estrogen receptor, raising concerns about potential unintended consequences. This research highlights the need for continued research and transparency regarding the safety and efficacy of herbal supplements, ensuring that consumers are informed about potential risks and benefits as they navigate the vast landscape of dietary choices.

Date :
  1. Date Completed 2015-04-16
  2. Date Revised 2020-09-29
Further Info :

Pubmed ID

25878948

DOI: Digital Object Identifier

PMC4397262

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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