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Post-marketing monitoring of intussusception after rotavirus vaccination in Japan.
Author: BauchauVincent, BuyseHubert, HollKatsiaryna, MahauxOlivia, SugiyamaKeiji, Van HolleLionel
Original Abstract of the Article :
PURPOSE: Rotarix(TM) was launched in November 2011 in Japan to prevent rotavirus gastroenteritis. Some studies suggest that Rotarix(TM) may have a temporal association with a risk of intussusception (IS). We assessed a possible association between IS and Rotarix(TM) vaccination in Japan. METHODS: A...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736691/
データ提供:米国国立医学図書館(NLM)
Rotavirus Vaccination and Intussusception: A Closer Look at Post-Marketing Surveillance
The implementation of [rotavirus vaccination] has been a significant milestone in public health, like a life-saving oasis in a desert ravaged by disease. However, as with any new intervention, [safety surveillance] is crucial. This research explores the potential association between [rotavirus vaccination] and [intussusception], utilizing [post-marketing monitoring data] to assess the risk. The authors analyze [observed versus expected cases] of [intussusception] in [Japan] following the introduction of [Rotarix(TM)]. Their findings provide insights into the potential risks and benefits of [rotavirus vaccination].
Rotavirus Vaccination: Weighing the Benefits and Risks
The authors find a [statistically significant excess] of [intussusception] cases within [7 days] following the [first dose] of [Rotarix(TM)]. However, they observe no such association with the [second dose]. It's like navigating a desert with potential hazards along the way. While the benefits of [rotavirus vaccination] are undeniable, it's important to be aware of the [potential risks]. This research underscores the importance of [ongoing post-marketing surveillance] to ensure the safety and effectiveness of [vaccines].
Vaccination Decisions: A Balancing Act Between Risks and Benefits
The authors' findings highlight the need for [informed decision-making] regarding [vaccination]. It's important to [weigh the potential benefits and risks] of any vaccine, considering your individual circumstances and discussing your concerns with a [healthcare professional]. Remember, vaccination is one of the most effective ways to protect yourself and your loved ones from [preventable diseases]. However, it's important to be aware of the potential side effects and discuss them with your doctor.
Dr.Camel's Conclusion
This research is a reminder that the journey through [vaccine development and implementation] is not without its challenges. While [rotavirus vaccination] has been a tremendous success, it's important to remain vigilant about potential risks and continue to monitor the safety of this crucial public health intervention. It's like building a safe haven in the desert, ensuring that the benefits outweigh the risks and that everyone has access to safe and effective vaccines.
Date :
- Date Completed 2016-03-31
- Date Revised 2021-01-09
Further Info :
Related Literature
English
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