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[Prophylaxis of vitamin D deficiency in hypothyroidism in the newborn infant].

Author: CzernichowP, FarriauxJ P, GarabedianM, LegerJ, TauC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of children with hypothyroidism found that vitamin D should be administered cautiously during the first 6 months of treatment, as it significantly increased the risk of hypercalcemia.
Paper Details　
Original Abstract of the Article :
This study deals with the relationship between the occurrence of hypercalcemia and the administration of prophylactic doses of vitamin D in children with hypothyroidism, before and during L-thyroxine (LT4) treatment. The goal of the study was to determine the dosage of vitamin D necessary to prevent...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2604508

データ提供：米国国立医学図書館（NLM）

Vitamin D Deficiency in Hypothyroid Infants: A Balancing Act

The field of [neonatal endocrinology] deals with the delicate balance of hormones in newborns. This study focuses on the potential for [vitamin D deficiency] in [hypothyroid infants], investigating the appropriate dosage of vitamin D to prevent [rickets] without inducing [hypercalcemia]. The researchers conducted a study to determine the optimal vitamin D dosage for infants with hypothyroidism.

Finding the Right Dose for Tiny Patients

The researchers found that [23% of hypothyroid infants] had [hypercalcemia] at the time of diagnosis. The risk of hypercalcemia increased to [70%] when vitamin D was administered during the first three months of [L-thyroxine (LT4)] treatment. This highlights the need for careful monitoring and individualized dosing of vitamin D in hypothyroid infants.

A Balancing Act Between Deficiencies and Excess

Just as a camel must balance its water intake in the desert, clinicians must find the right balance when treating vitamin D deficiency in hypothyroid infants. This study emphasizes the importance of a careful and individualized approach to prevent both vitamin D deficiency and hypercalcemia.

Dr.Camel's Conclusion

This study underscores the importance of careful monitoring and individualized dosing of vitamin D in hypothyroid infants. It's a reminder that finding the right balance is crucial in the delicate world of neonatal endocrinology.

Date :
  1. Date Completed 1990-02-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2604508

DOI: Digital Object Identifier

2604508

Related Literature

Article Analysis
・Effective treatment of vitamin d deficiency
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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