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Ursodeoxycholic Acid Can Improve Liver Transaminase Quantities in Children with Anticonvulsant Drugs Hepatotoxicity: a Pilot Study.
Author: AsgarshiraziMasoumeh, DaliliHosein, KeihanidoostZarrin, ShariatMamak
Original Abstract of the Article :
The present study has been directed to investigate Ursodeoxycholic Acid (UDCA) effect in children, to reduce the high Liver transaminases induced by Anticonvulsant drugs (drug induced hepatitis). This idea has been driven from Cytoprotective and antioxidant properties of UDCA to be used in drug indu...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/26069172
データ提供:米国国立医学図書館(NLM)
Ursodeoxycholic Acid: A Potential Solution for Anticonvulsant-Induced Liver Toxicity in Children
Anticonvulsant medications play a vital role in managing epilepsy, but they can sometimes lead to liver toxicity, particularly in children. This research explores the potential of ursodeoxycholic acid (UDCA) to reduce liver transaminase levels in children experiencing anticonvulsant-induced hepatotoxicity. The study investigated the effects of UDCA in a group of epileptic children who had elevated liver transaminases. The findings indicate that UDCA is effective and well-tolerated in children with drug-induced hypertransaminasemia.
UDCA: A Potential Ally in Protecting Young Liver
The research offers hope for children experiencing anticonvulsant-induced liver toxicity. The study's findings suggest that UDCA could be a safe and effective treatment option for reducing liver transaminase levels in these young patients. Further research is needed to confirm the long-term benefits of UDCA and to determine its optimal dosage for different age groups.
Protecting the Vulnerable: A Focus on Children's Health
Imagine a camel mother protecting her young calf from the harsh desert environment. That's the image that comes to mind when considering the importance of protecting the health of children. This research underscores the importance of finding safe and effective solutions for managing potential drug-related side effects, particularly in vulnerable populations like children. The study's findings offer a promising approach to mitigating the risk of anticonvulsant-induced liver toxicity, contributing to the well-being of young patients.
Dr.Camel's Conclusion
Children are particularly vulnerable to the effects of medications, and anticonvulsant-induced liver toxicity presents a significant concern. This research offers a ray of hope, suggesting that UDCA could be a valuable tool for reducing liver transaminase levels in these young patients. It's a testament to the ongoing quest for safe and effective treatments that protect the health and well-being of our youngest and most vulnerable individuals.
Date :
- Date Completed 2015-12-29
- Date Revised 2018-12-02
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